Mother Tongue can be said to be a poetic novel or long prose poem that combines the themes of Latina spirituality, erotics, and activism. This novel, which embodies the author’s identity and vision as a political activist, is subversive in that it depicts a colorful decolonial Latina single mother-the Virgin Mary-who desires and acts while resisting the bleached image of the Holy Virgin Mary from colonial imaginary. This study reads Demetria Martinez’s postmodern coming of age novel as the Conocimiento Narrative of Gloria Anzaldua, a Latina-style rite of healing and development and focuses particularly on the spiritual journey of the Millennial Goddess-to-be. The Conocimiento Narrative to acquire the aura of the immortal Guadalupe, transforming from the victim to the spiritual activist, naturally resonates with the author’s poem “Hail Mary.” In addition, the herstory of Mother Tongue rewrites the history of the Holy Family and converges it with the aesthetic portrait of the Millennial Virgin Mary.