Earticle

초록

영어

Background: In this study, the complexities of step-and-shoot intensity-modulated radiation therapy (IMRT) plans in magnetic resonance-guided radiation therapy systems were evaluated. Materials and Methods: Overall, 194 verification plans from the abdomen, prostate, and breast sites were collected using a 60Co-based ViewRay radiotherapy system (ViewRay Inc. , Cleveland, OH, USA). Various plan complexity metrics (PCMs) were calculated for each verification plan, including the modulation complexity score (MCS), plan-averaged beam area (PA), plan-averaged beam irregularity, plan-averaged edge (PE), plan-averaged beam modulation, number of segments, average area among all segments (AA/Seg), and total beam-on time (TBT). The plan deliverability was quantified in terms of gamma passing rates (GPRs) with a 1 mm/2% criterion, and the Pearson correlation coefficients between GPRs and various PCMs were analyzed. Results and Discussion: For the abdomen, prostate, and breast groups, the average GPRs with the 1 mm/2% criterion were 77.8 ± 6.0%, 79.8 ± 4.9%, and 84.7 ± 7.3%; PCMs were 0.263, 0.271, and 0.386; PAs were 15.001, 18.779, and 35.683; PEs were 1.575, 1.444, and 1.028; AA/Segs were 15.37, 19.89, and 36.64; and TBTs were 18.86, 19.33, and 5.91 minutes, respectively. The various PCMs, i.e. , MCS, PA, PE, AA/Seg, and TBT, showed statistically significant Pearson correlation coefficients of 0.416, 0.627, −0.541, 0.635, and −0.397, respectively, with GPRs. Conclusion: The area-related metrics exhibited strong correlations with GPRs. Moreover, the AA/Seg metric can be used to estimate the IMRT plan accuracy without beam delivery in the 60Co-based ViewRay radiotherapy system.

목차

ABSTRACT
Introduction
Materials and Methods
1. Data Selection and Treatment Planning
2. Measurements and Gamma Analysis
3. Plan Complexity Metrics
4. Statistical Analysis
Results and Discussion
Conclusion
Conflict of Interest
Acknowledgements
Author Contribution
References

키워드

저자

• Minsoo Chun [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea ]
• Ohyun Kwon [ Department of Medical Physics, University of Wisconsin, Madison, WI, USA ]
• Jong Min Park [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea, Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Korea ]
• Jung-in Kim [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629