Earticle

초록

영어

A goat that had been grazing was found dead. Autopsy found needle-like substances presumed to be yew leaves in the stomach, and yew ingestion was suspected. In the screening using gas chromatography-mass spectrometry(GC–MS), 3,5-dimethoxyphenol, the aglycone of taxicatine which is a typical ingredient of yew leaves, was identified as indirect evidence of yew ingestion, and toxicological analysis for compounds of yew, taxoids, was performed based on liquid–liquid extraction, followed by liquid chromatography–quadrupole time-of-flight mass spectrometry(LC–QTOF–MS) without reference standards. Using the analytical method, we determined six taxoids, namely taxine B, cephalomannine, paclitaxel, 10-deacetyltaxol (10-DAT), baccatin III, and 10-deacetylbaccatin III(10-DAB III), in the stomach contents. Based on these results of toxicological analysis, especially the determination of taxine B, and morphological finding, yew poisoning was proven as the cause of death.

목차

Abstract
Ⅰ. Introduction
Ⅱ. Case history
Ⅲ. Materials and methods
1. Reagents and chemicals
2. Sample preparation
3. LC–QTOF–MS conditions
4. GC–MS conditions
Ⅳ. Results and discussion
Ⅴ. Conclusion
Ⅵ. References

키워드

저자

• Dongeun Park [ Forensic Toxicology & Chemistry, Daejeon Institute, National Forensic Service, Daejeon, Republic of Korea ]
• Sanghee Woo [ Forensic Toxicology & Chemistry, Daejeon Institute, National Forensic Service, Daejeon, Republic of Korea ]
• Hyejin Chang [ Forensic Toxicology & Chemistry, Daejeon Institute, National Forensic Service, Daejeon, Republic of Korea ]
• Suncheun Kim [ Forensic Toxicology & Chemistry, Daejeon Institute, National Forensic Service, Daejeon, Republic of Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국법과학회지 [Korean Journal of Forensic Science]

• 간기

  반년간

• pISSN

  1598-0715

• 수록기간

  2000~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 367 DDC 347