Earticle

초록

영어

Background: Migraine is a common neurological disorder that affects the quality of life and causes several health problems. Preventive migraine treatment can reduce migraine frequency, headache severity, and health care costs. This study aimed to estimate the utilization of migraine preventive therapy and associated factors in eligible patients. Methods: We studied 534 patients with migraine who were eligible for migraine preventive therapy using 2017 National Patient Sample (NPS) data from the Health Insurance Review and Assessment Service (HIRA). We estimated the migraine days by calculating the monthly average number of defined daily dose (DDD) of migraine-specific acute drug. Patients with a monthly average number of DDD of 4 or more were considered as subjects for preventive treatment. Chi-square test and multiple logistic regression analysis were used to determine the association between the preventive therapy and the influencing variables. Results: Less than half of the eligible patients for prophylaxis (n=234, 43.8%) were prescribed preventive therapy. Multiple logistic regression results show that migraine preventive therapy was influenced by age, the type of migraine, and some comorbidities. Patients over the age of 50 tend to receive less prophylactic treatment than under the age of 40. On the other hand, migraine patients with epilepsy or depression were more likely to receive preventive therapy. Sumatriptan was the most preferred medication for acute treatment, and propranolol was the most commonly prescribed drug for prevention. Conclusions: More than half of the patients who were candidates for migraine prophylaxis were not receiving suitable preventive treatment. Positive factors affecting the use of migraine prevention were the presence of comorbidities such as epilepsy and depression.

목차

ABSTRACT
Methods
Data Source
Study Population
Candidates for migraine prophylaxis
Medication utilization of migraine-specific acute and preventive treatment
Statistical analysis
Results
Characteristics of study subjects
Preventive therapy utilization rate
Predictors of preventive therapy utilization
Patterns of acute and preventive therapy for migraine
Discussion
Conclusions
Acknowledgment
Conflict of Interest
References
Appendix A. Disease and Drug Codes

키워드

저자

• Yewon Kim [ College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea ]
• Susin Park [ College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea ]
• Eonjeong Kim [ College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea ]
• Nam Kyung Je [ College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615