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Abstracts for poster Presentation

Comprehensive functional analysis of putative glycosylation-related genes in the plant pathogenic fungus Fusarium graminearum

첫 페이지 보기
  • 발행기관
    한국당과학회 바로가기
  • 간행물
    한국당과학회 학술대회 바로가기
  • 통권
    2020 한국당과학회 연례학술대회(온라인) (2021.01)바로가기
  • 페이지
    pp.60-60
  • 저자
    Hee Ji Moon, Soyoung Choi, Jiyeun Park, Sieun Kim, Nahyun Lee, Yejin Choi, Ji Young Shin, Jung-Eun Kim, Hokyoung Son
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A390461

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원문정보

초록

영어
Glycosylation contributes to various molecular and cellular functions such as protein folding, localization, secretion, cell signaling, and communication by transferring glycans to proteins or lipids. Glycoproteins are expected to play essential roles for various biological processes including pathogenicity and reproductions in fungi; however, little is known about glycosylation process in filamentous fungi, especially in plant pathogenic fungi. The plant pathogenic fungus Fusarium graminearum causes a devastating disease called Fusarium head blight (FHB) on cereal crops. In addition to grain yield losses, infection of this pathogen causes severe contamination of mycotoxins, which are harmful to human and animal health. To understand molecular mechanisms underlying development and pathogenesis of this fungus, putative 78 N or O-glycosylation-related gene (GLY) knockout mutant library is being generated and we have successfully obtained 53 deletion mutations till now. Phenotypic changes, such as vegetative growth, sexual and asexual reproduction, and virulence of the mutants are being analyzed. Some mutants showed severe phenotypic defects suggesting that individual GLY gene plays important roles in this fungus. The ongoing works are focusing on the elucidation of the potential roles of GLY genes in diverse biological processes, such as fungal virulence, mycotoxin production and we are also analyzing glycan structure of glycoproteins in F. graminearum. This study is the first comprehensive functional analysis of GLY gene in plant pathogenic fungi, and it will be the fungal glycobiome study initiative.

저자

  • Hee Ji Moon [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea ]
  • Soyoung Choi [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea ]
  • Jiyeun Park [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea ]
  • Sieun Kim [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea ]
  • Nahyun Lee [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea ]
  • Yejin Choi [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea ]
  • Ji Young Shin [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea ]
  • Jung-Eun Kim [ Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea ]
  • Hokyoung Son [ Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국당과학회 [Korean Society for Glycoscience]
  • 설립연도
    2006
  • 분야
    의약학>약학
  • 소개
    본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.

간행물

  • 간행물명
    한국당과학회 학술대회
  • 간기
    연간
  • 수록기간
    2006~2022
  • 십진분류
    KDC 517 DDC 614

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