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Antimicrobial Effect of Supercritical Robinia pseudo-acacia Leaf Extracts and Its Transdermal Delivery System with Cell Penetrating Peptide

첫 페이지 보기
  • 발행기관
    국제문화기술진흥원 바로가기
  • 간행물
    International Journal of Advanced Culture Technology(IJACT) KCI 등재 바로가기
  • 통권
    Volume 8 Number 1 (2020.03)바로가기
  • 페이지
    pp.226-235
  • 저자
    Soo Hyeon Heo, Su In Park, Jinseo Lee, Miok Kim, Moon Sam Shin
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A372359

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원문정보

초록

영어
In this paper, we present to evaluate physiological activity of Robinia pseudo-acacia leaf and its skin penetration using liposome and cell penetrating peptide. After extraction with Robinia pseudo-acacia leaf using the distilled water and supercritical, various physiological activities were examined. In antioxidants experiments, the total concentration of polyphenol compounds was determined to be 56.88 mg/g in hydrothermal extract, 45.07 mg/g in supercritical extract. The DPPH radical scavenging ability at 1,000 μg/mL was 33.97% in supercritical extract. The scavenging effect on SOD experiment at 500 μg/mL was 76.41% in supercritical extract. In the antimicrobial experiments, the hydrothermal extract had no effect, but supercritical extract represented maximum clear zone of 14.00 mm in Staphylococcus aureus strain. Liposome containing the RSE (Robinia pseudo-acacia leaf supercritical extract) reduced particle size and stabilized zeta potential. In the epidermal permeability experiment, it was confirmed that the permeation of liposome containing the RSE and cell penetrating peptides was remarkable.

목차

Abstract
1. Introduction
2. Materials and methods
1. Instruments and reagents
2. Sample extraction
3. Antioxidant activity measurement
4. Antimicrobial experiment
5. Liposome making method
6. Measurement of particle size and zeta potential
7. Skin penetration experiment
8. Statistical processing
3. Result
1. Yield
2. Antioxidant efficacy of Robinia pseudo-acacia leaf
3. Antimicrobial experiment
4. Measurement of particle size and zeta potential
5. Skin penetration experiment
4. Conclusions
References

키워드

Robinia pseudo-acacia Supercritical Antimicrobial Cell Penetrating Peptide Cosmetics

저자

  • Soo Hyeon Heo [ Master Student, Department of Senior Healthcare majoring in Cosmetic Pharmacology, Eulji Univ. ]
  • Su In Park [ Doctorial Student, Department of Senior Healthcare majoring in Cosmetic Pharmacology, Eulji Univ. ]
  • Jinseo Lee [ Master Student, Department of Senior Healthcare majoring in Cosmetic Pharmacology, Eulji Univ. ]
  • Miok Kim [ Professor, Department of Beauty Design, Shin Ansan Univ., Korea. ]
  • Moon Sam Shin [ Professor, Department of Senior Healthcare majoring in Cosmetic Pharmacology, Eulji Univ., Korea ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    국제문화기술진흥원 [The International Promotion Agency of Culture Technology]
  • 설립연도
    2009
  • 분야
    공학>공학일반
  • 소개
    본 진흥원은 문화기술(Culture Technology) 관련 산·학·연·관으로 구성된 비영리 단체이다. 문화기술(CT)은 정보통신기술(ICT), 문화적 사고 기반의 예술, 인문학, 디자인, 사회과학기술이 접목된 신융합기술(New Convergence Technology, NCT)로 정의한다. 인간의 삶의 질을 향상시키고, 진보된 방향으로 변화시키고, 문화기술 관련 분야의 학술 및 기술의 발전과 진흥에 공헌하기 위하여, 제3조의 필요한 사업을 행함을 그 목적으로 한다.

간행물

  • 간행물명
    International Journal of Advanced Culture Technology(IJACT)
  • 간기
    계간
  • pISSN
    2288-7202
  • eISSN
    2288-7318
  • 수록기간
    2013~2025
  • 등재여부
    KCI 등재
  • 십진분류
    KDC 600 DDC 700

이 권호 내 다른 논문 / International Journal of Advanced Culture Technology(IJACT) Volume 8 Number 1

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