I.P. Shanura Femando, Thilina U. Jayawardena, Hyun-Soo Kim, A.P.J.P. Vaas, H.I.C. De Silva, C.M. Nanayakkara, D.T.U. Abeytunga, WonWoo Lee, Ginnae Ahn, Dae-Sung Lee, In-Kyu Yeo, You-Jin Jeon
언어
영어(ENG)
URL
https://www.earticle.net/Article/A370428
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목차
ABSTRACT 1. Introduction 2. Materials and methods 2.1. Characterization of CPM 2.2. Purification of fucosterol from Sargasswn binderi 2.3. Evaluation of inhibitory effects of fucosterol on elastase and collagenase 2.4. Cell lines 2.5. The culture of HaCaT and HDF cells 2.6. Cell viability and ROS 2.7. Evaluation of nuclear morphology 2.8. Western blot analysis 2.9. Analysis of cellular collagenase and elastase activity and MMP levels 2.10. Statistical analysis 3. Results 3.1. Size and composition of CPM 3.2. Protective effects of fucosterol against CPM-induced ROS production and apoptotic body formation 3.3. Protective effects of fucosterol against CPM- induced MMP production 3.4. Anti-inflammatory functionalities of fucosterol in HaCaT cells 3.5. Effect of preconditioned HaCaT cell culture media on HDF cell inflammatory responses 4. Discussions 5. Conclusions Acknowledgments References
I.P. Shanura Femando [ Department of Marine Life Sciences, jeju National University, Department of Marine Bio-Food Scrences, Chonnam National University ]
Thilina U. Jayawardena [ Department of Marine Life Sciences, jeju National University ]
Hyun-Soo Kim [ Department of Marine Life Sciences, jeju National University ]
A.P.J.P. Vaas [ Department of Chemistry, University of Colombo, Colombo 3, Sri Lanka ]
H.I.C. De Silva [ Department of Chemistry, University of Colombo, Colombo 3, Sri Lanka ]
C.M. Nanayakkara [ Department of Plant Sciences, University of Colombo, Colombo 3, Sri Lanka ]
D.T.U. Abeytunga [ Department of Chemistry, University of Colombo, Colombo 3, Sri Lanka ]
WonWoo Lee [ Department of Marine Life Sciences, jeju National University, Freshwater Bioresources Utilization Division, Nakdonggang National lnstitute of Biological Resources ]
Ginnae Ahn [ Department of Marine Bio-Food Scrences, Chonnam National University ]
Dae-Sung Lee [ Department of Applied Research, National Marine Biodiversity lnstitute of Korea ]
In-Kyu Yeo [ Department of Marine Life Sciences, jeju National University ]
Corresponding author
You-Jin Jeon [ Department of Marine Life Science, Jeju National University, Marine Science lnstitute, Jeju National University, Jeju Self-Governing Province 63333, Republic of Korea ]
제주대학교 해양과학연구소 [Marine Science Institute Jeju National University]
설립연도
1968
분야
농수해양>수산학
소개
해양의 실체와 그 자원의 합리적 이용과 관리방법을 규명하기 위하여 해양물리, 화학, 생물, 지질, 공학등 여러 관련분야에 관한 다양한 연구를 수행하며, 환경의 보전과 보호를 위해서 수질, 대기, 상·하수도, 폐기물, 사회적 환경 등의 연구를 통하여 쾌적하고 청정한 환경을 보전하기 위한 다양한 연구를 수행하고, 또한 해양 및 환경분야의 우수한 인력양성, 국내외 학술교류의 증진, 학·산 협동체제의 확립 등을 통하여 해양과 환경에 관한 기초 및 응용적 학술연구를 종합적으로 수행함을 목적으로 한다.
간행물
간행물명
해양과학연구소 연구논문집 [Bulletin of the Marine Science Institute]