Culture Convergence (CC)
The anti-oxidant activities of processed fruits and vegetables in APAP induced oxidative stress in BALB/c mice
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- 발행기관
- 국제문화기술진흥원 바로가기
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- 간행물
- International Journal of Advanced Culture Technology(IJACT) KCI 등재 바로가기
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- 통권
- Volume 7 Number 4 (2019.12)바로가기
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- 페이지
- pp.118-124
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- 저자
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- 언어
- 영어(ENG)
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- URL
- https://www.earticle.net/Article/A368006
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
- 영어
- There is a strong connection between the diet rich in antioxidants and the decreased incidence of cardiovascular and cancerous diseases. Diets that are rich in anti-oxidants particularly include fruits and vegetables containing the high amounts of vitamin A-E, carotenoids, and minerals. Different processing conditions applied for vegetables and plants results in the alteration of the nutrients present in them. Therefore the rationale of our study was to compare the antioxidant effects of different processed vegetables and plants and to see that which one of them showed best anti-oxidant activity. For this purpose, we have used acetaminophen induced oxidative stress model in mice to check the effects of processed apple, pear, carrot, cabbage, broccoli and radish. Our results have shown that the administration of these samples effectively decreased the expression of parameters related with oxidative stress like ALT, AST, catalase, superoxide dismutase, GPx and 8-OHdG. Moreover they also significantly protected the mice livers from APAP induced damage as shown by histological changes. Therefore our results have demonstrated the effects of processed fruits and vegetables in mice model of oxidative stress.
목차
Abstract
1. INTRODUCTION
2. EXPERIMENT MATERIALS AND METHODS
2.1. Preparation of Processed fruits and vegetables Extract
2.2. Experimental animals and sample administration
2.3. Assessment of serum 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels
2.4. Preparation of liver homogenate
2.5. Measurement of antioxidant enzyme levels in liver tissue
2.6. Evaluation of liver damage by serum biochemical analysis
2.7. Hematoxylin & Eosin (H&E) staining for liver tissueThe liver tissue was harvested from mice after euthanasia and
2.8. Statistical analysis
3. RESULT AND DISCUSSION
3.1. Amelioration in the activity of ALT and AST by fruits and vegetables samples:
3.2. Restoration of the levels of SOD, GPx and catalase activity by fruits and vegetables samples:
3.3. Reduction in the levels 8-OHdG by fruits and vegetables samples
3.4. Effects of fruits and vegetables samples on APAP induced hepatic damage
5. CONCLUSION
ACKNOWLEDGMENTS
REFERENCES
키워드
Anti-oxidant activity Vegetables fruits APAP mice저자
간행물 정보
발행기관
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- 발행기관명
- 국제문화기술진흥원 [The International Promotion Agency of Culture Technology]
- 설립연도
- 2009
- 분야
- 공학>공학일반
- 소개
- 본 진흥원은 문화기술(Culture Technology) 관련 산·학·연·관으로 구성된 비영리 단체이다. 문화기술(CT)은 정보통신기술(ICT), 문화적 사고 기반의 예술, 인문학, 디자인, 사회과학기술이 접목된 신융합기술(New Convergence Technology, NCT)로 정의한다. 인간의 삶의 질을 향상시키고, 진보된 방향으로 변화시키고, 문화기술 관련 분야의 학술 및 기술의 발전과 진흥에 공헌하기 위하여, 제3조의 필요한 사업을 행함을 그 목적으로 한다.
간행물
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- 간행물명
- International Journal of Advanced Culture Technology(IJACT)
- 간기
- 계간
- pISSN
- 2288-7202
- eISSN
- 2288-7318
- 수록기간
- 2013~2025
- 등재여부
- KCI 등재
- 십진분류
- KDC 600 DDC 700
이 권호 내 다른 논문 / International Journal of Advanced Culture Technology(IJACT) Volume 7 Number 4
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