Earticle

초록

영어

In recent years, there has been an increasing number of people taking hemp seeds (HS), especially imported HS, instead of nut for health care purposes in Korea. In addition, there is a growing awareness of whether delta 9-tetrahydrocannabinol (THC), a hallucinogenic component of cannabis, can be detected in urine when taking commercially available HS products. Thus, it is important to determine whether delta 9-tetrahydrocannabinol carboxylic acid (THC-COOH) is detected in the urine of people taking commercially available HS products and, if detected, the concentration of THC-COOH detected in urine 2 - samples of cannabis abusers and HS product onsumers, it is necessary to review.Thus, in this study, we analyzed the content of THC in the HS by purchasing two HS products (HS1 & HS2) in market. In addition, 13 volunteers were recruited, 6 for male and 7 for female. HS1(THC low level contained product, 1.58 mg/g) and HS2(THC high level contained product, 5.18 mg/g) were administered to each 3 male and female volunteers once a day for 28 days at a dose of 30 g, respectively. And one female administered same dose of mixed nuts (MN) for control. Urine samples of 13 volunteers were collected on the day before taking the HS or MN, once every week for 28 days. For THC analysis in HS, 1g of HS was added to THC-d3 as an internal standard and methanol, and extracted using ultrasonic device for 2 hour. This process was repeated three times. The COBAS C311 was used to screen the urine samples, and GC/MS was used to determine the amount of THC-COOH. THC-COOH levels in volunteers’urine ranged from 0 to 11 ng/mL. During the volunteers’ 28-day period, all of the THC-COOH were under the cutoff level. Therefore, this study is expected to be a good answer and basic study on the questions related to the consumption of HS products, as well as establishing the criteria for detection of THC-COOH in the urine of consumers of HS and cannabis abusers.

목차

Abstract
I. 서론
II. 실험 방법
1. 시료
2. 복용방법
3. 장비 및 시약
III. 실험 방법
IV. 결론
V. 감사의 글
VI. 참고문헌

키워드

저자

• 백승경 [ Seung-Kyung Baeck | 국립과학수사연구원 법독성학과 ] Corresponding author
• 김병주 [ Byung-Joo Kim | 국립과학수사연구원 법독성학과 ]
• 조병석 [ Byung-Suk Cho | 국립과학수사연구원 법독성학과 ]
• 김춘삼 [ Chun-Sam Kim | 국립과학수사연구원 법독성학과 ]
• 조한수 [ Han-Soo Cho | 국립과학수사연구원 법독성학과 ]
• 윤상준 [ Sang-Jun Yun | 국립과학수사연구원 법독성학과 ]
• 김은미 [ Eun-Mi Kim | 국립과학수사연구원 법독성학과 ]
• 인상환 [ Sang Hwan-In | 국립과학수사연구원 법독성학과 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국법과학회지 [Korean Journal of Forensic Science]

• 간기

  반년간

• pISSN

  1598-0715

• 수록기간

  2000~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 367 DDC 347