Earticle

초록

영어

Doxycycline is frequently prescribed to treat urogenital infections or acne vulgaris. A 39-year-old man was prescribed doxycycline as a treatment for his skin infection. He took each tablet on an empty stomach in the morning, and just before going to bed with insufficient water. After taking the prescribed medication for approximately 3 weeks, he was diagnosed with esophageal ulcer. He had not experienced these symptoms before, and the drug label says that doxycycline rarely causes esophageal ulcer. After discontinuing the medication, the symptoms disappeared. Using the World Health Organization-Uppsala Monitoring Center criteria, the causality for doxycycline-induced esophageal ulcer was evaluated as “possible.” Additionally, using the Naranjo scale and Korean causality assessment algorithm (Ver. 2), the causality was evaluated as “probable.” Previous reports have stated that most patients who took doxycycline with insufficient water just before going to bed or in the supine position developed esophageal ulcer. Therefore, all patients taking doxycycline must be provided with detailed instructions about the appropriate administration methods.

목차

ABSTRACT
증례 보고
인과성 평가
고찰
결론
참고문헌

키워드

저자

• 김가연 [ Ga Yeon Kim | 가천대학교 약학대학 ]
• 이찬희 [ Chan Hee Lee | 가천대학교 약학대학 ]
• 이정우 [ Jeong Woo Lee | 가천대학교 약학대학 ]
• 이정민 [ Jung-Min Lee | 대한약사회 지역의약품안전센터 ]
• 이모세 [ Mo-Se Lee | 대한약사회 지역의약품안전센터 ]
• 지은희 [ Eunhee Ji | 가천대학교 약학대학 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615