Farhad Safari Zanjani, Abbas Ali Gaeni, Dicle Aras, Cengiz Akalan
언어
영어(ENG)
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https://www.earticle.net/Article/A360030
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초록
영어
The roots of apoptosis caused by the use of certain drugs in patients with colorectal cancer and certain drugs could be induced the change in genes SSTR2 and SSTR5. SSTRs play a role in colorectal cancer and it’s also known that exercise training has similar effects to certain drugs. Therefore, this study aims to evaluate the effects of a combined training program on hormonal and physiological changes in patients with colorectal cancer. Twenty patients with colorectal cancer were in-cluded in this study and divided into two groups as experimental (n=10) and control (n=10). The experimental group performed an exercise training program 5 days a week for 14 weeks. Blood samples were tak-en from the patients before and after the training program, and analyzed for somatostatin and its receptors. When the pretest effect excluded as statistical, there were no significant differences in SSRT2 (P>0.05) and SSRT5 (P>0.05) between the experimental and control groups. The hy-pothesis for this study was “SSTR2 and SSTR5 will improve after com-bined training program” however, in accordance with the results it was rejected. It seems that the determined training program for these pa-tients need to be extended and performed for at least 3 months in a gradual incremental structure so that it could affect their health indica-tors significantly.
목차
Abstract INTRODUCTION MATERIALS AND METHODS Research methodology Exercise training protocol Laboratory method Statistical analysis RESULTS DISCUSSION CONFLICT OF INTEREST REFERENCES
키워드
SomatostasinSSTRColorectal cancerCombined training
저자
Farhad Safari Zanjani [ Department of Physical Education and Sport Sciences, Faculty of Education, IA University Zanjan Branch, Zanjan, Iran ]
Abbas Ali Gaeni [ Department of Exercise Physiology, Faculty of Sport Sciences, Tehran University, Tehran, Iran ]
Dicle Aras [ Department of Coaching Education, Faculty of Sport Sciences, Ankara University, Ankara, Turkey ]
Corresponding Author
Cengiz Akalan [ Department of Coaching Education, Faculty of Sport Sciences, Ankara University, Ankara, Turkey ]