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Original Article

The effect of strength and endurance training on SSTR2 and SSTR5 in patients with colorectal cancer

첫 페이지 보기
  • 발행기관
    한국운동재활학회 바로가기
  • 간행물
    JER SCOPUS KCI 등재 바로가기
  • 통권
    Vol.15 No.4 (2019.08)바로가기
  • 페이지
    pp.622-627
  • 저자
    Farhad Safari Zanjani, Abbas Ali Gaeni, Dicle Aras, Cengiz Akalan
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A360030

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초록

영어
The roots of apoptosis caused by the use of certain drugs in patients with colorectal cancer and certain drugs could be induced the change in genes SSTR2 and SSTR5. SSTRs play a role in colorectal cancer and it’s also known that exercise training has similar effects to certain drugs. Therefore, this study aims to evaluate the effects of a combined training program on hormonal and physiological changes in patients with colorectal cancer. Twenty patients with colorectal cancer were in-cluded in this study and divided into two groups as experimental (n=10) and control (n=10). The experimental group performed an exercise training program 5 days a week for 14 weeks. Blood samples were tak-en from the patients before and after the training program, and analyzed for somatostatin and its receptors. When the pretest effect excluded as statistical, there were no significant differences in SSRT2 (P>0.05) and SSRT5 (P>0.05) between the experimental and control groups. The hy-pothesis for this study was “SSTR2 and SSTR5 will improve after com-bined training program” however, in accordance with the results it was rejected. It seems that the determined training program for these pa-tients need to be extended and performed for at least 3 months in a gradual incremental structure so that it could affect their health indica-tors significantly.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
Research methodology
Exercise training protocol
Laboratory method
Statistical analysis
RESULTS
DISCUSSION
CONFLICT OF INTEREST
REFERENCES

키워드

Somatostasin SSTR Colorectal cancer Combined training

저자

  • Farhad Safari Zanjani [ Department of Physical Education and Sport Sciences, Faculty of Education, IA University Zanjan Branch, Zanjan, Iran ]
  • Abbas Ali Gaeni [ Department of Exercise Physiology, Faculty of Sport Sciences, Tehran University, Tehran, Iran ]
  • Dicle Aras [ Department of Coaching Education, Faculty of Sport Sciences, Ankara University, Ankara, Turkey ] Corresponding Author
  • Cengiz Akalan [ Department of Coaching Education, Faculty of Sport Sciences, Ankara University, Ankara, Turkey ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국운동재활학회 [Korean Society of Exercise Rehabilitation]
  • 설립연도
    2004
  • 분야
    의약학>재활의학
  • 소개
    한국운동재활학회는 사회적, 정신적, 신체적 통합건강복지 이론의 학술연구와 회원 상호간 학술교류 증진을 장려함으로써 학문적 발전을 도모하고 나아가 건강복지선진국 발전에 이바지함을 목적으로 한다.

간행물

  • 간행물명
    JER [Journal of Exercise Rehabilitation]
  • 간기
    격월간
  • pISSN
    2288-176X
  • eISSN
    2288-1778
  • 수록기간
    2013~2026
  • 등재여부
    SCOPUS,KCI 등재
  • 십진분류
    KDC 517 DDC 613

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