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※ 학술발표대회집, 워크숍 자료집 중 4페이지 이내 논문은 '요약'만 제공되는 경우가 있으니, 구매 전에 간행물명, 페이지 수 확인 부탁 드립니다.
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The aim of this study was to investigate the serum serotonin, prolactin, and plasma dopamine levels in humans with and without caffeine in-gestion during and after passive heat loading (half immersion in 42°C hot water). Thirty male volunteers participated in the randomized exper-iment (control group, n=15 vs. caffeine ingestion group, n=15, 3 mg/kg). After 60 min, passive heat loading was conducted for 30 min. Blood samples were collected and assessed for serum serotonin, dopamine and prolactin with and without caffeine during and after passive heat loading. Serum serotonin was significantly lower in the caffeine inges-tion group compared to the control group after passive heat loading for 30 min (Post) (P<0.05) and also after 60 min of resting (P<0.01). Dopa-mine and prolactin were significantly higher in the caffeine ingestion group than in the control group at the Post time point (P<0.001). In con-clusion, 3-mg/kg caffeine ingestion prior to passive heat loading can al-ter central serotonergic and dopaminergic activity, which may contrib-ute to reduced central fatigue and subsequently, to reduced general fa-tigue. Prolactin responses during passive heat loading were also sig-nificantly related to caffeine ingestion in this study. However, the inhibi-tory effects of dopamine on prolactin by caffeine remain to be elucidated.
목차
Abstract INTRODUCTION MATERIALS AND METHODS Subjects Measurement and experimental procedure Passive heat loading Serotonin, dopamine, and prolactin level analysis Data analyses RESULTS Serotonin Dopamine Prolactin DISCUSSION CONFLICT OF INTEREST ACKNOWLEDGMENTS REFERENCES