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Original Article

Ingestion of caffeine links dopamine and 5-hydroxytryptamine release during half immersion in 42°C hot water in a humans

첫 페이지 보기
  • 발행기관
    한국운동재활학회 바로가기
  • 간행물
    JER SCOPUS KCI 등재 바로가기
  • 통권
    Vol.15 No.4 (2019.08)바로가기
  • 페이지
    pp.571-575
  • 저자
    Jeong-Beom Lee, Tae-Wook Kim
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A360022

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초록

영어
The aim of this study was to investigate the serum serotonin, prolactin, and plasma dopamine levels in humans with and without caffeine in-gestion during and after passive heat loading (half immersion in 42°C hot water). Thirty male volunteers participated in the randomized exper-iment (control group, n=15 vs. caffeine ingestion group, n=15, 3 mg/kg). After 60 min, passive heat loading was conducted for 30 min. Blood samples were collected and assessed for serum serotonin, dopamine and prolactin with and without caffeine during and after passive heat loading. Serum serotonin was significantly lower in the caffeine inges-tion group compared to the control group after passive heat loading for 30 min (Post) (P<0.05) and also after 60 min of resting (P<0.01). Dopa-mine and prolactin were significantly higher in the caffeine ingestion group than in the control group at the Post time point (P<0.001). In con-clusion, 3-mg/kg caffeine ingestion prior to passive heat loading can al-ter central serotonergic and dopaminergic activity, which may contrib-ute to reduced central fatigue and subsequently, to reduced general fa-tigue. Prolactin responses during passive heat loading were also sig-nificantly related to caffeine ingestion in this study. However, the inhibi-tory effects of dopamine on prolactin by caffeine remain to be elucidated.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
Subjects
Measurement and experimental procedure
Passive heat loading
Serotonin, dopamine, and prolactin level analysis
Data analyses
RESULTS
Serotonin
Dopamine
Prolactin
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES

키워드

Caffeine Dopamine Passive heat loading Prolactin Sero-tonin

저자

  • Jeong-Beom Lee [ Department of Physiology, College of Medicine, Soonchunhyang University, Cheonan, Korea ]
  • Tae-Wook Kim [ Department of Physiology, College of Medicine, Soonchunhyang University, Cheonan, Korea ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국운동재활학회 [Korean Society of Exercise Rehabilitation]
  • 설립연도
    2004
  • 분야
    의약학>재활의학
  • 소개
    한국운동재활학회는 사회적, 정신적, 신체적 통합건강복지 이론의 학술연구와 회원 상호간 학술교류 증진을 장려함으로써 학문적 발전을 도모하고 나아가 건강복지선진국 발전에 이바지함을 목적으로 한다.

간행물

  • 간행물명
    JER [Journal of Exercise Rehabilitation]
  • 간기
    격월간
  • pISSN
    2288-176X
  • eISSN
    2288-1778
  • 수록기간
    2013~2026
  • 등재여부
    SCOPUS,KCI 등재
  • 십진분류
    KDC 517 DDC 613

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