Yong Jin Park, Jisu Jeong, Jae Seok Kim, Dong Soo Choi, Goang-Won Cho, Jin Seong Park, Jong Kuk Lim
언어
영어(ENG)
URL
https://www.earticle.net/Article/A358959
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원문정보
초록
영어
Staphylococcus epidermidis is well-known not only as an innocuous normal flora species commonly isolated from human skin, but also as an important bacterial species to keep skin healthy, because this species can protect the human skin from pathogenic microorganisms. However, S. epidermidis turns into a potential pathogen in damaged skin, because these bacteria can easily form a biofilm on the wound area and provide antimicrobial resistance to other microorganisms embedded in the biofilm. Thus, it is important to kill S. epidermidis in the early stage of wound treatment and block the formation of biofilms in advance. In the present study, hydrogel wound dressings were fabricated using polyvinyl alcohol/ polyethylene glycol containing silver citrate nanorods, which have been proven to have strong antimicrobial activity, especially against S. epidermidis, and their wound-healing efficacy was investigated in vivo using a rat experiment.
목차
Abstract 1. Introduction 2. Materials and Methods 2.1 Synthesis of Antimicrobial Reagents (Silver Citrate Compounds) 2.2 Preparation of Wound Dressing Containing Silver-Citrate Compounds 2.3 Measuring the Mechanical Properties of Hydrogel Wound Dressings 2.4 Cell Culture 2.5 Cytotoxicity Test 2.6 Rat Clinical Experiment 3. Results and Discussion 4. Conclusions References
Yong Jin Park [ Department of Medicine, College of Medicine, Chosun University ]
Jisu Jeong [ Department of Chemistry, College of Natural Science, Chosun University ]
Jae Seok Kim [ Department of Chemistry, College of Natural Science, Chosun University ]
Dong Soo Choi [ Post-Harvest Engineering Division, National Institute of Agricultural Sciences, Jeonju 54875, Korea ]
Goang-Won Cho [ Department of Biology, College of Natural Science, Chosun University, Department of Life Science, BK21-Plus Research Team for Bioactive Control Technology, Chosun. University, Gwangju, Korea ]
Corresponding Author
Jin Seong Park [ Department of Materials Engineering, College of Engineering, Chosun University ]
Corresponding Author
Jong Kuk Lim [ Department of Chemistry, College of Natural Science, Chosun University ]
Corresponding Author
조선대학교 기초과학연구원 [The Natural Science Research Institute of Chosun]
설립연도
2008
분야
자연과학>자연과학일반
소개
본 연구원은 기초과학을 진흥하기 위한 연구·교육 및 그 보급을 목적으로 한다. 이 목적을 달성하기 위하여 다음 각 호의 사업을 수행한다.
1. 기초과학 제 분야에 관한 조사와 연구
2. 기초과학에 관한 학술행사(학술대회, 학술세미나, 심포지엄, 초청강연회 등) 개최
3. 학문후속세대 및 일반인을 위한 기초과학 교육
4. 기관지『조선자연과학논문지』 발간
5. 『자연과학연구총서』, 『자연과학번역총서』 등 단행본 발간
6. 기타 본 연구원의 목적과 관련된 사업
간행물
간행물명
통합자연과학논문집(구 조선자연과학논문집) [Journal of Integrative Natural Science]