Earticle

초록

영어

Background: To monitor proton beam in proton therapy, prompt gamma imaging systems are being developed by several research groups, and these systems are expected to improve the quality of the treatment and the patient safety. To apply the prompt gamma imaging systems into spot scanning proton therapy, the systems should be able to monitor the proton beam range of a spot with a small number of protons ( <108 protons), which is quite often not the case due to insufficient prompt gamma statistics. Materials and Methods: In the present study, we propose to improve prompt gamma statistics by merging the prompt gamma distributions of several individual spots into a new distribution. This proposal was tested by Geant4 Monte Carlo simulations for a multi-slit prompt gamma camera which has been developed to measure the proton beam range in the patient. Results and Discussion: The results show that the proposed method clearly enhance the statistical precision of beam range measurement. The accuracy of beam range verification is improved, within ~1.4 mm error, which is not achievable before applying the developed method. Conclusion: In this study, we tried to improve the statistics of the prompt gamma statistics by merging the prompt gamma distributions of multiple spots, and it was found that the merged distribution provided sufficient prompt gamma statistics and the proton beam range was determined accurately.

목차

ABSTRACT
Introduction
Materials and Methods
1. Merging of prompt gamma distributions
2. Geant4 simulations
3. Test cases
Results and Discussion
1. Precision of beam range determination before applying developed method
2. Combination of prompt gamma distributions in the same energy layer
3. Combination of prompt gamma distributions at the same beam location
Conclusion
Acknowledgements
References

키워드

저자

• Sung Hun Kim [ Department of Nuclear Engineering, Hanyang University, Seoul, Korea ]
• Jong Hoon Park [ Department of Nuclear Engineering, Hanyang University, Seoul, Korea ]
• Youngmo Ku [ Department of Nuclear Engineering, Hanyang University, Seoul, Korea ]
• Hyun Su Lee [ Department of Nuclear Engineering, Hanyang University, Seoul, Korea ]
• Young-su Kim [ Department of Nuclear Engineering, Hanyang University, Seoul, Korea ]
• Chan Hyeong Kim [ Department of Nuclear Engineering, Hanyang University, Seoul, Korea ] Corresponding Author
• Jong Hwi Jeong [ Proton Therapy Center, National Cancer Center, Goyang, Korea ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629