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Poster Presentation : Implantation / Uterine Biology

Localization of Conceptus-derived for Uterus, CYP19A1, IL1B, IFND and IFNG during the Peri-Implantation Period in Pigs

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    Reproductive & Developmental Biology(Supplement) 바로가기
  • 통권
    Volume 41 No 2 Supplement (2017.06)바로가기
  • 페이지
    pp.75-75
  • 저자
    Soogil Chae, Inkyu Yoo, Jisoo Han, Hwanhee Jang, Soohyung Lee, Hakhyun Ka
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A347565

원문정보

초록

영어
For successful pregnancy, the appropriate interactions between the maternal endometrium and the implanting conceptus are essential during the implantation period. In pigs, the implanting conceptus produces estrogens, interleukin 1 beta (IL1B), interferon delta (IFND) and interferon gamma (IFNG) during early pregnancy. Estrogens are produced by CYP19A1, a key enzyme for estrogen biosynthesis, and play a role in maternal recognition of pregnancy in pigs. IL1B is known to be involved in production and transport of prostaglandins in the endometrium. The role of IFND and IFNG during the implantation period is not fully understood. Also, localization of CYP19A1, IL1B, IFND and IFNG in the implanting conceptus is not fully understood. Thus, this study determined the localization of these molecules in conceptus during the peri-implantation period in pigs. We performed in situ hybridization and immunohistochemistry using conceptus on Days 12 and 15 of pregnancy. CYP19A1 were detected mainly in trophectoderm of conceptus on Days 12 and 15 of pregnancy. IL1B was expressed in trophectoderm of Day 12, but not Days 15. IFND mRNA and protein were localized to trophectoderm and endoderm of Days 12 and 15 with stronger immunostaining signal on trophectoderm than endoderm. IFNG mRNA and protein were mainly localized to trophectoderm, but not endoderm, on Days 12 and 15 of pregnancy. These results showed that CYP19A1, IL1B, IFND and IFNG were localized to conceptus, suggesting that these molecules secreted from conceptus during the peri-implantation period are dynamically regulated during conceptus development in pigs. Further study is needed to analyze the function of these molecules in the uterine endometrium during early pregnancy.

키워드

Pig Conceptus CYP19A1 IL1B Interferon

저자

  • Soogil Chae [ Division of Biological Science and Technology, Yonsei University ]
  • Inkyu Yoo [ Division of Biological Science and Technology, Yonsei University ]
  • Jisoo Han [ Division of Biological Science and Technology, Yonsei University ]
  • Hwanhee Jang [ Division of Biological Science and Technology, Yonsei University ]
  • Soohyung Lee [ Division of Biological Science and Technology, Yonsei University ]
  • Hakhyun Ka [ Division of Biological Science and Technology, Yonsei University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    Reproductive & Developmental Biology(Supplement)
  • 간기
    연간
  • 수록기간
    2001~2017
  • 십진분류
    KDC 527 DDC 636

이 권호 내 다른 논문 / Reproductive & Developmental Biology(Supplement) Volume 41 No 2 Supplement

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