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Poster Presentation : Implantation / Uterine Biology

Expression and Regulation of S100A15A in the Uterine Endometrium and Placenta in Pigs

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    Reproductive & Developmental Biology(Supplement) 바로가기
  • 통권
    Volume 41 No 2 Supplement (2017.06)바로가기
  • 페이지
    pp.74-74
  • 저자
    Hwanhee Jang, Deokhan Ko, Inkyu Yoo, Jisoo Han, Soogil Chae, Soohyung Lee, Hakhyun Ka
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A347564

원문정보

초록

영어
S100 protein family is small calcium-binding proteins with EF-hand motif and comprises more than 20 proteins in human. S100 proteins are involved in intracellular and/ or extracellular signaling, such as proliferation, differentiation, apoptosis, calcium homeostasis, inflammation and migration. Previously, we have shown that the expression of S100A15A mRNA in the endometrium is increased on Day 12 of pregnancy compare to the estrous cycle. However, the expression and regulation of S100A15A have not been determined in the uterine endometrium during the estrous cycle and pregnancy in pigs. Therefore, we analyzed the expression and regulation of S100A15A mRNA in the uterine endometrium during the estrous cycle and pregnancy. Real-time RT-PCR analysis showed that S100A15A mRNA was expressed in the uterine endometrium during the estrous cycle and pregnancy with higher levels on Day 12 of pregnancy than the estrous cycle. To investigate the effects of steroid hormones and interleukin 1 beta (IL1B) on the expression of S100A15A mRNA, endometrial tissue explants from Day 12 of the estrous cycle were treated with steroid hormones, estradiol and progesterone, or IL1B. The levels of S100A15A mRNA were increased by estradiol and IL1B. These results showed that S100A15A was expressed in the uterine endometrium in a pregnancy stage-specific manner and the expression of S100A15A was regulated by estradiol and IL1B of conceptus origin, suggesting that S100A15A may play a key role in the establishment of pregnancy in pigs.

키워드

Pig Uterus Implantation S100A15A

저자

  • Hwanhee Jang [ Division of Biological Science and Technology, Yonsei University ]
  • Deokhan Ko [ Division of Biological Science and Technology, Yonsei University ]
  • Inkyu Yoo [ Division of Biological Science and Technology, Yonsei University ]
  • Jisoo Han [ Division of Biological Science and Technology, Yonsei University ]
  • Soogil Chae [ Division of Biological Science and Technology, Yonsei University ]
  • Soohyung Lee [ Division of Biological Science and Technology, Yonsei University ]
  • Hakhyun Ka [ Division of Biological Science and Technology, Yonsei University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    Reproductive & Developmental Biology(Supplement)
  • 간기
    연간
  • 수록기간
    2001~2017
  • 십진분류
    KDC 527 DDC 636

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