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Poster Presentation : Gene Expression / Function

Effect of Silver Nanoparticles to F9 Cells about Anti Cancer and Induce Differentiation of Cancer Stem Cells

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    Reproductive & Developmental Biology(Supplement) 바로가기
  • 통권
    Volume 41 No 2 Supplement (2017.06)바로가기
  • 페이지
    pp.41-41
  • 저자
    Jae woong Han, Abu Musa Md Talimur Reza, Yun-Jung Choi
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A347539

원문정보

초록

영어
Silver nanoparticles (AgNPs) is one of the nanomaterials as most popular and commonly used in consumer products in biomedical devices, antibiotic agent, wound dressings, text tile and also candidate of anti-cancer material. F9 cell, the teratocarcinoma stem cell line has been widely used as a model for the analysis of molecular mechanisms associated with differentiation and retinoic acid (R.A) is well known molecule that induce F9 cell differentiation. There are many study about induce differentiation in stem cells by AgNPs and in anti-cancer therapy, induce cancer stem cell differentiation is very important to killing cancer. In this study, we demonstrated that AgNPs showing toxicity in F9 cells as anti-cancer cell effect and also induce F9 cell differentiation. F9 cells are induce cell toxicity and apoptosis after treated AgNPs and also make F9 cell differentiation like induced by R.A. Signaling pathway analysis showing that gene and protein expression going different and more sensetive to anti cancer drug, cisplatin, after induced differentiation by AgNPs. We found that potential of AgNPs as not only killing cancer but also make cancer stem cell going to differentiation.

키워드

Silver nanoparticles Cancer stem cell Differentiation Cell toxicity

저자

  • Jae woong Han [ Department of Stem Cell and Regenerative Biotechnology, Konkuk University ]
  • Abu Musa Md Talimur Reza [ Department of Stem Cell and Regenerative Biotechnology, Konkuk University ]
  • Yun-Jung Choi [ Department of Stem Cell and Regenerative Biotechnology, Konkuk University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    Reproductive & Developmental Biology(Supplement)
  • 간기
    연간
  • 수록기간
    2001~2017
  • 십진분류
    KDC 527 DDC 636

이 권호 내 다른 논문 / Reproductive & Developmental Biology(Supplement) Volume 41 No 2 Supplement

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