Earticle

초록

영어

Embryo development is the most important time in the life of a multicellular organism because the limited cells of the embryo produce all the cells of the adult body. And transcription factors are transcriptional regulatory proteins that specifically bind to the transcriptional regulatory region DNA and activate or inhibit the transcription of that gene. It is change in the stage of embryo development that positions and levels of expression of transcription factors. Therefore, we know that transcription factors conduct vary crucial role in the stage of embryo development. So, if we could identify clearly changes of transcription factors, it can be very helpful in understanding the mechanism of embryo development. We experimented in transcription factors from GV oocyte to blastocyst how are expressed in porcine. We focused on especially pluripotency genes, which play an important role in early embryo development. So we conducted to immuno- staining using antibodies of Cdx2, Oct4, Sox2, Nanog, and E-Cadherin. Unfortunately we used mouse’s antibody because pig`s antibody against transcription factors did not exist. We checked five transcription factors (Cdx2, Oct4, Sox2, Nanog and E-Cadherin) in early embryo development in porcine. We found different expression patterns between mouse and pig in some stages. Therefore, we need to experiment that different patterns of transcription factors play a role in species, and why occur.

키워드

저자

• Joo Bin Lee [ Department of Animal Science & Biotechnology, Chungnam National University, Daejeon, Republic of Korea ]
• Tao Lin [ Department of Animal Science & Biotechnology, Chungnam National University, Daejeon, Republic of Korea ]
• Hyeon Yeong Shin [ Department of Animal Science & Biotechnology, Chungnam National University, Daejeon, Republic of Korea ]
• Jae Eun Lee [ Department of Animal Science & Biotechnology, Chungnam National University, Daejeon, Republic of Korea ]
• Jung won Kang [ Department of Animal Science & Biotechnology, Chungnam National University, Daejeon, Republic of Korea ]
• So Yeon Kim [ Department of Animal Science & Biotechnology, Chungnam National University, Daejeon, Republic of Korea ]
• Dong Il Jin [ Department of Animal Science & Biotechnology, Chungnam National University, Daejeon, Republic of Korea ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  발생공학 국제심포지엄 및 학술대회 [International Symposium on Developmental Biotechnology]

• 간기

  연간

• 수록기간

  2004~2018

• 십진분류

  KDC 527 DDC 636