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Expression of Factors Involved Embryo Quality is Correlated Genes in Endometrial Epithelial Cells with Different Types of Bovine Embryos

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    발생공학 국제심포지엄 및 학술대회 바로가기
  • 통권
    2018년 한국동물번식학회, 한국수정란이식학회 공동학술대회 (2018.06)바로가기
  • 페이지
    pp.16-16
  • 저자
    Enkhbolor Barsuren, Sang-Hwan Kim, Ho-Jun Lee, Jong-Taek Yoon
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A347422

원문정보

초록

영어
In mammals, the uterus is the organ of pregnancy. In most mammals, conceptus implantation to the uterine endometrium consists of blastocyst hatching, migration, apposition/ attachment, invasion and subsequent placental formation. It is known that close to 50% of fertilized pre-implantation embryos in mammals, including humans, fail to implant. We hypothesized that there was the embryo quality-dependent expression of embryo development associated genes on Endometrial Epithelial Cells (EECs) of superovulated Hanwoo. Therefore examined to study the mode of EECs expression during pre-implantation. Additionally, we investigated how EECs respond to the presence of embryos by FSH and LH in bovine EECs in vitro(The EECs were divided into three different groups as follows good (n=4), fair (n=4), bad (n=2)). Our results found that the different expression of EST mRNA to each the group. In addition, it was found that the expression of genes related to MMP-9 and development showed different appearance in each group, and the result of embryo development was different. In particular, the expression of genes associated with the growth of cells from the Good group was very high, and the expression of genes affecting cell activity was also very high. However, Bad group had a high expression of Casp-3 protein and expression of metabolism-related genes of other cells was very low. Also, it is interesting that the expression of FSH and LH in the EEC of Good group is very high, and even in the evaluation of the development rate of in vitro fertilized egg using co-curture, the expression of genes related to cellular metabolic processes increases It was confirmed. These results suggest that FSH and LH and cellular action increase the metabolism of EEC and also increase the development of Embryo.

키워드

Endometrial Pre-implantation Bovine Embryo

저자

  • Enkhbolor Barsuren [ Major in the Animal Biotechnology the Graduate School of Biology & Imformation Technology, Hankyong National University, Anseong 17579, Korea ]
  • Sang-Hwan Kim [ Institute of Genetic Engineering, Hankyong National University, Ansung 17579, Korea ]
  • Ho-Jun Lee [ Department of Animal Life Research, Hankyong National University, Anseong 17579, Korea ]
  • Jong-Taek Yoon [ Institute of Genetic Engineering, Hankyong National University, Ansung 17579, Korea, Department of Animal Life Research, Hankyong National University, Anseong 17579, Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    발생공학 국제심포지엄 및 학술대회 [International Symposium on Developmental Biotechnology]
  • 간기
    연간
  • 수록기간
    2004~2018
  • 십진분류
    KDC 527 DDC 636

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