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Poster Presentation : Oocyte Maturation / Embryonic Development

Increased Apoptosis in Pig Parthenogenetic Fetuses Resulting Fetal Degeneration during Early Gestation Period

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    발생공학 국제심포지엄 및 학술대회 바로가기
  • 통권
    The 17th International Symposium on Developmental Biotechnology (2017.10)바로가기
  • 페이지
    pp.91-91
  • 저자
    In-Sul Hwang, Seung-Chan Lee, Tae-Uk Kwak, Mi-Ryung Park, Sun-A Ock, Keon Bong Oh, Jae-Seok Woo, Gi-Sun Im, Seongsoo Hwang
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A347360

원문정보

초록

영어
Parthenogenetic embryo without contribution of paternal genome would be terminated during early gestation period in pigs. Therefore, the present study was designed to analyze the characteristics of parthenogenetic fetuses to identify the possible causes for fetal degeneration during early gestation period. In brief, the pig parthenogenetic fetuses were produced by embryo transfer of parthenogenetic embryos into surrogates. Then, the pig parthenogenetic fetuses were recovered at day 26 and 35 of gestation and conducted to analyze histological characteristics. In results, the parthenogenetic pig fetuses were generated and recovered at day 26 and 35 successfully. The size of parthenogenetic fetuses (n=15, 1.5 cm) recovered at day 26 of gestation were significantly smaller than normal fetuses (n=18, 2.0 cm) while the weights were comparable (0.36 vs. 0.51 g). The size and weight of parthenogenetic fetuses (n=9, 1.8 cm, 0.47 g) recovered at day 35 of gestation were significantly lower than normal fetuses (n=3, 3.67 cm, 3.71 g). The paraffin-embedded sections from parthenogenetic fetus at day 26 showed normal formation of major organs while parthenogenetic fetus at day 35 showed terminated and degenerated formation of major organs. Additionally, the apoptotic cell number of parthenogenetic fetuses (4.4) recovered at day 35 of gestation were significantly (p<0.05) higher than normal fetuses (2.0) while the result of day 26 of gestation showed comparable (1.8 vs. 2.0). Conclusively, our results can suggest that increased apoptosis in fetal tissues also leads to abnormal development of parthenogenetic pig fetus resulting delayed development until day 26 and then termination and degeneration from day 36.

키워드

Fetal degeneration Apoptosis Parthenogenetic embryos

저자

  • In-Sul Hwang [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Seung-Chan Lee [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Tae-Uk Kwak [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Mi-Ryung Park [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Sun-A Ock [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Keon Bong Oh [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Jae-Seok Woo [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Gi-Sun Im [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]
  • Seongsoo Hwang [ Animal Biotechnology Division, National Institute of Animal Science, Wanju, Jeollabuk-do 55365, Republic of Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    발생공학 국제심포지엄 및 학술대회 [International Symposium on Developmental Biotechnology]
  • 간기
    연간
  • 수록기간
    2004~2018
  • 십진분류
    KDC 527 DDC 636

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