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Poster Presentation : Implantation / Uterine Biology

Differential Expression Patterns of PCD between Corpus Luteum in Normal and Miniature Porcine

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    발생공학 국제심포지엄 및 학술대회 바로가기
  • 통권
    The 17th International Symposium on Developmental Biotechnology (2017.10)바로가기
  • 페이지
    pp.83-83
  • 저자
    Ji-Hye Lee, Da-Hye Shin, Sang-Hwan Kim, Jong-Taek Yoon
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A347355

원문정보

초록

영어
There were differences in reproductive physiology between miniature pig and normal pig, suggesting differences in estrus and pregnancy. The importance of apoptosis in the development of ovarian follicles and maturation of oocytes. However little is known about the molecular mechanism behind these characteristics. It is known that proper execution of programmed cell death is crucial for normal follicular development. Especially, the plays a very important role of remodeling corpus luteum for successful fertilization to reproductive effect of mammals. In the present study of this experiment was to understand the programmed cell death in normal pig and miniature pig corpus luteum of estrus day 15. Expression of MAP1LC3A and other autophagy- related genes (ATG13, Beclin-1) was significantly higher in normal pig corpus luteum. On the other hand, the expression of apoptosis-related genes (casp-3, BAX) and BCL-2 gene was significantly higher in miniature pig corpus luteum. Expression of genes related to cell metabolism activity (IGF, PCNA) was significantly higher in the normal pig corpus luteum than in the miniature pig corpus luteum. Gene expression of hormone receptor (FSH, LH) was higher than that of miniature pig corpus luteum. Our result is suggest that the expression of LH and FSH hormone in the normal pig is elevated by the high activity of the cell-metabolizing activity gene, and thus, the autophagy is induced. In the miniature pig, the expression of the cell metabolizing activity gene is low and the progesterone hormone mechanism And BCL-2 gene expression are thought to induce apoptosis. This is normal pig and miniature pig corpus luteum of estrus day 15 were able to confirm that shows a significantly different pattern to each other. While the process of programmed cell death in normal pig corpus luteum majorly depended on the type II pathway (autophagy), miniature pig corpus luteum preferred the type I pathway (apoptosis). These differences may contribute greatly to manipulating the reproduction of pigs.

키워드

Apoptosis Autophagy Hormone Corpus luteum Porcine

저자

  • Ji-Hye Lee [ Major in the Animal Biotechnology The Graduate School of Biology & Imformation Technology, Hankyong National University, Anseong 456-749, Korea ]
  • Da-Hye Shin [ Department of Animal Life Research, Hankyong National University, Anseong 456-749, Korea ]
  • Sang-Hwan Kim [ Institute of Genetic Engineering, Hankyong National University, Ansung 456-749, Korea ]
  • Jong-Taek Yoon [ Institute of Genetic Engineering, Hankyong National University, Ansung 456-749, Korea, Department of Animal Life Research, Hankyong National University, Anseong 456-749, Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    발생공학 국제심포지엄 및 학술대회 [International Symposium on Developmental Biotechnology]
  • 간기
    연간
  • 수록기간
    2004~2018
  • 십진분류
    KDC 527 DDC 636

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