The 17th International Symposium on Developmental Biotechnology (2017.10)바로가기
페이지
pp.77-77
저자
Hoseung Kwak, Donghun Kang, Eunjoo Lee, Daeyoung Kim
언어
영어(ENG)
URL
https://www.earticle.net/Article/A347349
원문정보
초록
영어
Embryo transfer is one of the important process of assisted reproductive technology (ART) and that is associated with uterus endometrial receptivity. Recently, mouse endometrial stimulation by artificial injury had shown the favorable effect on conception. In this experiment, we used uterus stimulation method that injury the endometrium to increase implantation rate for spontaneous Diabetes Mellitus (sDM) rat. Rats are divided into several groups involved a control group. We performed the surgical method to experimental group bilaterally or unilaterally. After that, we investigated morphological change using immunohistochemical staining method and calculated implanted embryos respective sides of the uterus. The number of implanted embryo in the experimental group was significantly higher and there were lots of morphological changes including glands and endometrial cells that support implantation. Our results showed that sDM rat uterus endometrial injury in ART help enhancing implantation rate.