Tuyen Thi My Nguyen, NariSeo, YongkiKim, JiAJung, JaehanKim
언어
영어(ENG)
URL
https://www.earticle.net/Article/A346293
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Among the animal, human uniquely contains high amount and diverse structure of soluble oligosaccharides in milk. The multiple functions for infant of human milk oligosaccharides (HMOs) have been well discussed, particularly sialic acid and fucose containing oligosaccharide. The structure and composition of HMOs structure were diverse among different mothers or breastfeeding period of a given woman as well, and nutritional conditions. The geographical origin of mothers is one of the factors that influence on the HMOs diversity. Hence, we aim to profile HMOs from mothers in Korea, China and Vietnam in the relation to their nutritional status to provide a comprehensive understanding about HMOs from maternal in these countries. The results show that oligosaccharide composition of human milk varied among countries. HMOs from Korea and China were almost similar in term of degree of polymerization (DP) whereas Vietnam HMOs has lower DP3 but high in DP4 and DP5. The ratio of non-secretor mothers that were unable to produce α-1, 2-fucosylated glycans in their secretions, following by Vietnam and lowest in Korea population. The fucosylated, and sialylated HMOs were 62-67%, 4-6% in China and Korea milk respectively while 50% and 9.2% in Vietnam maternal milk. These observed proportion were different from earlier studies that may due to the difference in geographical origin of mothers. Elucidating molecular structure of HMOs provides an important opportunities for improving diet and health care for the neonate in specific region.
저자
Tuyen Thi My Nguyen [ Department of Food Nutrition, Chungnam National University, Daejeon ]
NariSeo [ Graduate School of Analytical and Technology, Chungnam National University, Daejeon ]
YongkiKim [ Maeil Asian Human Milk Research Center, Maeil Dairies Co., Ltd. ]
JiAJung [ Maeil Asian Human Milk Research Center, Maeil Dairies Co., Ltd. ]
JaehanKim [ Department of Food Nutrition, Chungnam National University, Daejeon ]
본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.