So-Jung Bang, Eun-Sook Lee, Cheon-Seok Park, Eun-Ji Song, Young-Do Nam, Dong-Ho Seo
언어
영어(ENG)
URL
https://www.earticle.net/Article/A346281
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원문정보
초록
영어
Raw potato starch-based feeds controlled body weight and insulin resistance in mice. To investigate the association of the phenotypic changes with an impact on the gut microbiota, various starches-based feeds formulated based on the nutritional composition of AIN93G but substituted corn starch to wheat, rice, or potato starch, were provided ad libitum 6 week-aged C57BL/6 male mice for 16 weeks. Profiles of microbiota in the mice’s feces were compared by analyzing16s rRNA gene amplicon sequencing and QIIME pipeline with Greengenes database. It found that gut microbiota was changed according to the kinds of starches. The ratio of Firmicutes to Bacteroidetes was decreased by feeding potato starch diet and taxonomy assignment showed that potato starch diet increased the abundances of Akkermansia, Rikenellaceae and Sutterella. The large intestine of mice fed potato starch-based diet was heavier than those of other starches-fed mice. According to the literatures, it reported that Akkermansia and Sutterella are associated with improvement of obesity and especially, Akkermansia known to be correlated with the abundance of Rikenellaceae have been demonstrated to induce an increase in the large intestine weight and an increase of insulin sensitivity. Therefore, it supposes that the effects of potato starch based-diet on body weight and related insulin resistance can be elucidated from the intestine microbial changes.
저자
So-Jung Bang [ Research group of gut microbiome, Korea Food Research Institute, Department of Food Science and Technology, Institute of Life Science & Resource, Kyung Hee University, Gyeonggi, Republic of Korea ]
Eun-Sook Lee [ Research group of gut microbiome, Korea Food Research Institute, Jeollabuk-do, Republic of Korea ]
Cheon-Seok Park [ Department of Food Science and Technology, Institute of Life Science & Resource, Kyung Hee University, Gyeonggi, Republic of Korea ]
Eun-Ji Song [ Research group of gut microbiome, Korea Food Research Institute, Jeollabuk-do, Republic of Korea, Department of Food Biotechnology, Korea University of Science and Technology, Daejeon, Republic of Korea ]
Young-Do Nam [ Research group of gut microbiome, Korea Food Research Institute, Jeollabuk-do, Republic of Korea ]
Dong-Ho Seo [ Research group of gut microbiome, Korea Food Research Institute, Jeollabuk-do, Republic of Korea ]
본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.