Earticle

초록

영어

Recently, there have been many efforts to develop new compounds having skin whitening effects from natural products. The aim of this study was to assess the availability of Asterubine extracted from Asterias amurensis as a skin whitener through the evaluation of the inhibitory effects of melanogenesis in B16F1 melanoma cells. B16F1 cells were treated with Asterubine extracted from Asterias amurensis (10, 100 and 1,000 μM/mL, respectively) and incubated for 72 hours. B16F1 cells were treated with Asterubine (10, 100 and 1,000 μM/mL, respectively) and α-melanocyte stimulating hormone (α-MSH), simultaneously, and incubated for 72 hours. Content of melanin synthesis and tyrosinase activity were determined. The expressions of tyrosinase was measured by Western blot analysis. Treatment with 100 and 1,000 μM/mL Asterubine significantly decreased tyrosinase activity by 11.4% and 27.7%, respectively, compared to Asterubine non-treated group (p<0.05). Treatment with 1,000 μM/mL Asterubine significantly decreased melanin synthesis by 26.5%, compared to α-MSH alone group (p<0.05). Asterubine significantly inhibited expressions of tyrosinase induced by α-MSH. In conclusion, these findings indicate that Asterubine extracted from Asterias amurensis, which inhibits melanin synthesis and tyrosinase expression, is an effective skin whitening agent.

목차

Abstract
Ⅰ. 서론
1. 연구 배경
2. 연구목적
Ⅱ. 이론적 배경
Ⅲ. 연구방법
1. 연구 모형
2. 설문지 구성
3. 분석설계방법
Ⅳ. 연구 결과 및 고찰
1. 조사대상자의 일반적 특성
2. 일반적 특성에 따른 교육만족도에 영향을 미치는 요인 간 차이검증 분석
3. 상관관계 분석
4. 회귀분석
Ⅴ. 결론
참고문헌

키워드

저자

• 김은숙 [ Eun Suk Kim | 진주보건대학교 피부미용과 ]
• 하명희 [ Myung Hee Ha | 진주보건대학교 피부미용과 ]
• 배성권 [ Sung Kwon Bae | 고신대학교 의료경영학과 ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  국제보건미용학회지 [Journal of Health and Beauty]

• 간기

  계간

• pISSN

  2005-369X

• eISSN

  2765-1347

• 수록기간

  2007~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 593 DDC 646