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Original Article

Effects of N-acetylcysteine supplementation on cellular damage and oxidative stress indicators in volleyball athletes

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  • 발행기관
    한국운동재활학회 바로가기
  • 간행물
    JER SCOPUS KCI 등재 바로가기
  • 통권
    Vol.14 No.5 (2018.10)바로가기
  • 페이지
    pp.802-809
  • 저자
    Alan de Jesus Pires de Moraes, Leonardo Vidal Andreato, Braulio Henrique Magnani Branco, Edson Luiz da Silva, Márcia Aparecida Gonçalves, Rafaella Zulianello dos Santos, Aline Minuzzi Becker, Luciana da Silveira Cavalcante, Fernanda da Silva Casagrande, Magnus Benetti
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A339266

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원문정보

초록

영어
The purpose of this study was to evaluate the effects of N-acetylcyste-ine (NAC) supplementation on cellular damage and oxidative stress in-dicators in volleyball athletes. Twenty male volleyball athletes at nation-al level performed a physical training session and were divided into 2 groups, which for 7 days took the placebo substance or NAC. After 7 days the athletes repeated the same training session. In both sessions, blood samples were collected 30 min before and immediately after the training session to measure cellular damage and oxidative stress mark-ers. The main results show that, although higher concentrations of glu-tathione peroxidase and superoxide dismutase were observed in post-session 1 than those in postsession 2, the other markers showed an in-crease in antioxidant action after supplementation of NAC, once the ef-fect of experimental conditions (P=0.030) were observed in: time effect (P<0.001) and interaction (P=0.019) for total glutathione; time effect (P<0.001) and interaction (P<0.001) for reduced glutathione; and time effect (P<0.001) for ferric-reducing antioxidant potential. The oxidant action indicated by the protein carbonyl was higher in the placebo group than in the NAC group (P=0.028), but a time effect (P<0.001) for the thiobarbituric acid reactive substances showed lower values in presession 1 than in presession 2. For the cellular damage markers, an-tagonistic results between markers were found. Based in the results, the supplementation of NAC during a short period was effective in re-ducing oxidant action and increasing antioxidant action. However, con-clusive alterations in the responses of the cellular damage markers were not obtained.

목차

Abstract
 INTRODUCTION
 MATERIALS AND METHODS
  Experimental design
  Participants
  Incremental treadmill test
  One-repetition maximum test
  Supplementation
  Dietary control
  Training sessions
  Blood samples and biochemical analysis
  Statistical analysis
 RESULTS
 DISCUSSION
 CONFLICT OF INTEREST
 REFERENCES

키워드

Sports Sports nutritional sciences Antioxidants

저자

  • Alan de Jesus Pires de Moraes [ Sciences Center of Health and Sport, State University of Santa Catarina, Florianópolis, Brazil, University of the Itajaí Valley, Itajaí, Brazil ] Corresponding author
  • Leonardo Vidal Andreato [ Sciences Center of Health and Sport, State University of Santa Catarina, Florianópolis, Brazil, Department of Physical Education, University Center of Maringa, Parana, Brazil ]
  • Braulio Henrique Magnani Branco [ Department of Physical Education, University Center of Maringa, Parana, Brazil, Postgraduate Program in Health Promotion, University Center of Maringá, Maringá, Brazil ]
  • Edson Luiz da Silva [ Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Brazil ]
  • Márcia Aparecida Gonçalves [ Sciences Center of Health and Sport, State University of Santa Catarina, Florianópolis, Brazil, University of the Itajaí Valley, Itajaí, Brazil ]
  • Rafaella Zulianello dos Santos [ Sciences Center of Health and Sport, State University of Santa Catarina, Florianópolis, Brazil, University of the Itajaí Valley, Itajaí, Brazil ]
  • Aline Minuzzi Becker [ Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Brazil ]
  • Luciana da Silveira Cavalcante [ Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Brazil ]
  • Fernanda da Silva Casagrande [ Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Brazil ]
  • Magnus Benetti [ Sciences Center of Health and Sport, State University of Santa Catarina, Florianópolis, Brazil ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국운동재활학회 [Korean Society of Exercise Rehabilitation]
  • 설립연도
    2004
  • 분야
    의약학>재활의학
  • 소개
    한국운동재활학회는 사회적, 정신적, 신체적 통합건강복지 이론의 학술연구와 회원 상호간 학술교류 증진을 장려함으로써 학문적 발전을 도모하고 나아가 건강복지선진국 발전에 이바지함을 목적으로 한다.

간행물

  • 간행물명
    JER [Journal of Exercise Rehabilitation]
  • 간기
    격월간
  • pISSN
    2288-176X
  • eISSN
    2288-1778
  • 수록기간
    2013~2026
  • 등재여부
    SCOPUS,KCI 등재
  • 십진분류
    KDC 517 DDC 613

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