Functional capacity and ventilatory efficiency are preserved in well-controlled people living with human immunodeficiency virus/acquired immunodeficiency syndrome
Luís Fernando Deresz, Marlus Karsten, Isadora Faraco Corrêa, Anelise Sonza, Maria Letícia Rodrigues Ikeda, Candissa Silva da Silva, Pedro Dal Lago
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https://www.earticle.net/Article/A336649
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To verify and compare the responses of the cardiopulmonary variables to the incremental test in physically inactive people living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) (PLWHA) with well-controlled disease and physically inactive healthy subjects (non-HIV/AIDS). Participants performed a cardiopulmonary exercise test (CPX) on a treadmill. Data were analyzed using the Mann–Whitney test and Spearman correlation. Nine PLWHA (5 women) and 9 non-HIV/AIDS gender and activity level-matched controls were included in the data analysis. Data are expressed in median (range). No difference was shown in the PLWHA group when compared to the control group in functional capacity (peak oxygen consumption [VO2peak]: 29.9 (20.9–36.4) mL/kg/min vs. 32.2 (24.5–39.4) mL/kg/ min) and ventilatory efficiency (oxygen uptake efficiency slope [OUES]: 2,058 [1,474–3,204] vs. 2,612 [1,383–4,119]; minute ventilation carbon dioxide production slope: 27.4 [22.5–33.6] vs. 27.5 [20.4–38.1]). The results are also similar to maximal heart rate, oxygen pulse, gas exchange threshold, respiratory compensation point, heart rate recovery, and half-time of VO2peak recovery. OUES had a strong correlation with VO2peak in the PLWHA group (rs= 0.70, P= 0.04) and control group (rs= 0.78, P= 0.02). The results of this study indicate that functional capacity and ventilatory efficiency in PLWHA with well-controlled disease are preserved and are not different from sedentary subjects. In this sense, when CPX is unavailable, the aerobic assessment and prescription could be based on simpler procedures used in healthy subjects.
목차
Abstract INTRODUCTION MATERIALS AND METHODS Study design and participants Cardiopulmonary exercise testing (CPX) Immunologic and virologic characteristics Data analyses RESULTS DISCUSSION CONFLICT OF INTEREST REFERENCES
Luís Fernando Deresz [ Post Graduation Program in Health Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil, Physical Education Department, Health Sciences Institute, Universidade Federal de Juiz de Fora, Governador Valadares, Brazil ]
Corresponding author
Marlus Karsten [ Physical Therapy Department, Universidade do Estado de Santa Catarina (UDESC), Florianópolis, Brazil ]
Isadora Faraco Corrêa [ Physical Therapy Department, UFCSPA, Porto Alegre, Brazil ]
Anelise Sonza [ Physical Therapy Department, Universidade do Estado de Santa Catarina (UDESC), Florianópolis, Brazil ]
Maria Letícia Rodrigues Ikeda [ Nursing Department, Universidade do Vale do Rio dos Sinos, São Leopoldo, Brazil, Health Secretariat of State of Rio Grande do Sul, Porto Alegre, Brazil ]
Candissa Silva da Silva [ Post Graduation Program in Health Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil ]
Pedro Dal Lago [ Post Graduation Program in Health Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil, 4Physical Therapy Department, UFCSPA, Porto Alegre, Brazil ]