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Original Article

Oral adenosine 5′-triphosphate supplementation improved hemodynamic and autonomic parameters after exercise in hypertensive women

첫 페이지 보기
  • 발행기관
    한국운동재활학회 바로가기
  • 간행물
    JER SCOPUS KCI 등재 바로가기
  • 통권
    Vol.14 No.4 (2018.08)바로가기
  • 페이지
    pp.671-679
  • 저자
    Marcelo Conrado de Freitas, Ana Laura Ricci-Vitor, Renan Valero Freire, Erico Chagas Caperuto, Luiz Carlos Marques Vanderlei, Fábio Santos Lira, Fabrício Eduardo Rossi
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A336648

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원문정보

초록

영어
The aim of this study was to verify the autonomic modulation and blood pressure after adenosine-5’-triphosphate (ATP) supplementation asso-ciated to acute aerobic exercise in hypertensive women. Eleven hyper-tensive women (age, 61.8±5.0 years) completed a randomized, double blind trial: ATP supplement condition (ATP=400 mg) or placebo. After 30 min of supplementation or placebo intake, the subjects performed 30 min of aerobic exercise (70%–75% of maximum heart rate). The auto-nomic modulation was assessed by heart rate variability during rest and recovery (postexercise until 30 min of recovery), the square root of the mean squared difference between adjacent RR intervals (RMSSD), standard deviation of successive values (SDNN), low frequency (LF) and high frequency (HF) were measured. The blood pressure (systolic blood pressure [SBP] and diastolic blood pressure, mmHg) were re-corded at rest, immediately postexercise, post-10, post-20, and post-30 min after exercise. For RMSSD, there was statistically significant differ-ence during recovery, with higher RMSSD for ATP compared to placebo (rest=16.4±8.5 vs. placebo=11.6±4.0; ATP=18.5±9.7 msec; P=0.020). When analyzing the delta (recovery minus rest), the RMSSD (ATP=2.1± 7.2 msec vs. placebo=-4.7±7.5 msec; P=0.009), LF (ATP=-19.8±122.7 vs. placebo=-94.1±200.2 msec2; P=0.02), and SDNN (ATP=-2.8±12.2 msec vs. placebo=-10.6±10.5 msec; P=0.010) were higher for ATP than placebo. Furthermore, there was a greater postexercise hypotension at 20 min for ATP (SBP: ATP=-13.2±8.4 mmHg vs. placebo=-6.1±9.9 mmHg; P=0.006). Acute ATP supplementation promoted greater postexercise hypotension for systolic blood pressure and induced faster recovery of heart rate variability in hypertensive women.

목차

Abstract
 INTRODUCTION
 MATERIALS AND METHODS
  Experimental design
  Subjects
  Procedures
  Blood pressure and autonomic modulation measurements
  Exercise protocol
  Statistical analysis
 RESULTS
 DISCUSSION
 CONFLICT OF INTEREST
 REFERENCES

키워드

Aerobic exercise ATP supplementation Nutrition Autonom-ic nervous system Hypertension

저자

  • Marcelo Conrado de Freitas [ Skeletal Muscle Assessment Laboratory (LABSIM), São Paulo State University (UNESP), School of Technology and Sciences, Department of Physical Education, Presidente Prudente, Brazil, Department of Nutrition, São Paulo Western University-UNOESTE, Presidente Prudente, Brazil ]
  • Ana Laura Ricci-Vitor [ Department of Physiotherapy, São Paulo State University (UNESP), Presidente Prudente, Brazil ]
  • Renan Valero Freire [ Skeletal Muscle Assessment Laboratory (LABSIM), São Paulo State University (UNESP), School of Technology and Sciences, Department of Physical Education, Presidente Prudente, Brazil ]
  • Erico Chagas Caperuto [ University São Judas Tadeu, São Paulo, Brazil ]
  • Luiz Carlos Marques Vanderlei [ Department of Physiotherapy, São Paulo State University (UNESP), Presidente Prudente, Brazil ]
  • Fábio Santos Lira [ Exercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, Brazil ]
  • Fabrício Eduardo Rossi [ Immunometabolism of Skeletal Muscle and Exercise Research Group, Department of Physical Education, Federal University of Piauí (UFPI), Teresina, Brazil ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국운동재활학회 [Korean Society of Exercise Rehabilitation]
  • 설립연도
    2004
  • 분야
    의약학>재활의학
  • 소개
    한국운동재활학회는 사회적, 정신적, 신체적 통합건강복지 이론의 학술연구와 회원 상호간 학술교류 증진을 장려함으로써 학문적 발전을 도모하고 나아가 건강복지선진국 발전에 이바지함을 목적으로 한다.

간행물

  • 간행물명
    JER [Journal of Exercise Rehabilitation]
  • 간기
    격월간
  • pISSN
    2288-176X
  • eISSN
    2288-1778
  • 수록기간
    2013~2026
  • 등재여부
    SCOPUS,KCI 등재
  • 십진분류
    KDC 517 DDC 613

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