Maxine Helga Pinpin, Gian Paolo B. Sepulveda, Marian Camille C. Obrero, Ms. Rose Butaran
언어
영어(ENG)
URL
https://www.earticle.net/Article/A328911
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초록
영어
Most cardiovascular diseases (CVD) are caused by high levels of cholesterol and lipoproteins, specifically Low Density Lipoproteins (LDL), in the blood, heart and liver. In response to the growing number of patients with heart-related diseases, this study was conducted to determine the synergistic effects of coconut oil with the leading cholesterollowering medicine, atorvastatin on the lipid profile of guinea pigs (Cavia percellus), particularly the Total Cholesterol to high-density lipoprotein (TC: HDL) ratio, which is considered one of the best markers in determining CVD risk. After blood samples were taken for initial lipid analysis, the guinea pigs were subjected to four treatments: coconut oil, statins, statins with coconut, oil and a control group. After two weeks of administering the treatments, blood was extracted again for the new lipoprotein levels. Data was analyzed using two-way ANOVA (α = 0.05). Results show that decrease in the TC:HDL ratio induced by coconut oil was lower than the decrease induced by atorvastatin. Interestingly, the group with coconut oil and statins, yielded the greatest decrease in the TC: HCL ratio. This shows the positive synergy of coconut oil and statins in decreasing CVD risk. The information provided in this study will aid in the improvement of current medicine.
목차
ABSTRACT 1. INTRODUCTION 2. RESEARCH METHODS 2.1. Procurement of Guinea Pigs, Coconut Oil and Statins 2.2. Determination of Initial Lipoprotein Levels 2.3. Feeding of Coconut Oil and Statins 2.4. Determination of Final Lipoprotein levels 3. RESULTS AND DISCUSSION 3.1. Tables of Results 3.2. Discussion 4. CONCLUSION 5. RECOMMENDATIONS 6. ACKNOWLEDGEMENTS 7. REFERENCES
국제과학영재학회 [The Society for the International Gifted in Science]
설립연도
2006
분야
자연과학>자연과학일반
소개
과학영재를 위한 연구 활동을 통하여 과학영재를 발굴하고, 발굴된 과학영재가 과학 분야의 관련 연구 활동을 할 수 있도록 지원하여, 이들이 과학 관련 분야의 진로를 선택하도록 장려함으로써 국제경쟁력을 갖춘 우수 과학기술인을 배출하고 국가 경제발전 및 문화창달과 세계 과학 발전에 기여함을 목적으로 한다.
간행물
간행물명
APEC Youth Scientist Journal [APEC 청소년 과학학술지]
간기
반년간
pISSN
2005-5625
수록기간
2009~2022
십진분류
KDC 405DDC 505
이 권호 내 다른 논문 / APEC Youth Scientist Journal Vol. 4