Isabela Maia da Cruz Fernandes, Rafael Zambelli Pinto, Paulo Ferreira, Fábio Santos Lira
언어
영어(ENG)
URL
https://www.earticle.net/Article/A326709
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초록
영어
Low back pain is a health issue with significant impact to patients and society. This narrative review aims to synthesize the relationship be-tween obesity, low-grade inflammation and low back pain. It is known that a sedentary lifestyle is a risk factor for obesity and related disor-ders. The adipose tissue of obese people secretes a range of cytokines of character pro- and anti-inflammatory, with many molecular effects. In addition, pro-inflammatory cytokines are sensitizers of C-reactive protein (CRP), a marker of acute inflammation that can be linked to the musculoskeletal pain sensation individuals with back pain. Another in-flammatory marker deserves mention, prostaglandin E2. Prostaglandin E2 is important in the process of triggering actions such as pyrexia, sen-sation of pain and inflammation, which are exhibited in low back pain condition. The potential for exercises and physical activity to control these mediators and act as a preventative measure for back pain are important because they work as a nonpharmacological strategy to this target audience. There are two types of exercise discussed in this re-view, the moderate-intensity continuous training and high-intensity in-terval training.
목차
Abstract INTRODUCTION PREVALENCE ETIOLOGY SEDENTARY LIFESTYLE OBESITY ADIPOSE TISSUE AND INFLAMMATORY MARKERS PGE2 AND EXERCISE MODERATE-INTENSITY CONTINUOUS TRAINING HIGH-INTENSITY INTERVAL TRAINING CONCLUSIONS CONFLICT OF INTEREST ACKNOWLEDGMENTS REFERENCES
키워드
Low back painObesitySedentary lifestyleC-reactive proteinProstaglandins
저자
Isabela Maia da Cruz Fernandes [ Exercise and Immunometabolism Research Group, Department of Physical Education, Faculty of Sciences and Technology, São Paulo State University, Presidente Prudente, São Paulo, Brazil ]
Rafael Zambelli Pinto [ Department of Physical Therapy, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil ]
Paulo Ferreira [ Discipline of Physiotherapy, The University of Sydney – Faculty of Health Sciences, Sydney, Australia ]
Fábio Santos Lira [ Exercise and Immunometabolism Research Group, Department of Physical Education, Faculty of Sciences and Technology, São Paulo State University, Presidente Prudente, São Paulo, Brazil ]
Corresponding author