Earticle

초록

영어

Physical exercise may help maintain muscle properties and functional improvement after peripheral nerve lesion, which may be enhanced by using biocompatible substances, such as sericin. The aim of this study was analyse the effect of sericin associated with swimming exercise on the phenotype, innervation, and functionality of the plantar muscle of Wistar rats. Forty randomly divided adult rats were used in five groups of eight animals: control, injury, sericin, exercise, exercise and sericin. The application of sericin was done on the spot, 100 μL, shortly after nerve compression. Three days after sciatic nerve compression, the swimming and swimming and sericin groups were submitted to physical swimming exercise for 21 days. Afterwards, the animals were euthanised and the plantar muscle was dissected and submitted to histochemical and histoenzymological techniques. The grip strength test did not show alterations in muscular functionality, and the control presented greater muscle mass in relation to the other groups, the same did not occur for muscle length. Polymorphic neuromuscular junctions were detected in the groups, although without significant morphometric alterations of the area, major and minor diameters. The percentage of type I fibres was lower in the lesion group and there was no difference in fibres IIa and IIb between groups. The area of fibres I, IIa and IIb remained constant between groups. Sericin biopolymer combined with swimming exercise did not affect plantar muscle function, submitted to experimental axonotmosis, whose contractile properties were altered by nerve injury.

목차

Abstract
 INTRODUCTION
 MATERIALS AND METHODS
  Swimming exercise protocol with overload
  Evaluation of muscle grip strength
  Collection of the plantar muscle and histochemical and histoenzymological analyses
  Statistical analysis
 RESULTS
  Functional analysis and macroscopic parameters of the plantar muscle
  Morphological and morphometric analysis of NMJs
  Histoenzymological analysis of the plantar muscle
 DISCUSSION
 CONFLICT OF INTEREST
 REFERENCES

키워드

저자

• André Junior Santana [ Programa de Pós-Graduação em Biociências e Saúde da, Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ]
• Jean Carlos Debastiani [ Programa de Pós-Graduação em Biociências e Saúde da, Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ]
• Regina Inês Kunz [ Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ]
• Pamela Buratti [ Programa de Pós-Graduação em Biociências e Saúde da, Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ]
• Rose Meire Costa Brancalhão [ Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ]
• Lucinéia de Fátima Chasko Ribeiro [ Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ]
• Márcia Miranda Torrejais [ Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ]
• Gladson Ricardo Flor Bertolini [ Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel, Brazil ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613