Earticle

초록

영어

Mineral rich spring water has been used in spa and bathing purpose that often belong to traditional medicinal therapies. It also considered as a classical alternative medicine to cure the immunological disease. Recently, mineral rich containing medicine and cosmetics has been widely applied in hair loss purpose but not tried by mineral water. Therefore, the purpose of the present study is to observe the hair growth promoting effects of mineral rich spring water in SKH-1 hairless mice. We designed this study to evaluate the mineral water has hair growth promoting effect. The experimental SKH-1 hairless mice were divided into a normal control group (NC: No treatment), a positive control group (M: 3% Minoxidil), and different concentrations of mineral water group as a treatment group (MW: 2.5%, 5%, and 10%). All the test samples were topically sprayed on the three distinct parts of the leg, dorsal and a shoulder portion (about 1 cm2 areas) of the mice skin (100 L per application), twice a day, for μ 21 days. The number of hair and length was measured by taking a photograph of using the scale bar tools of the DinoCapture 2.0 digital microscope windows software. The thickness of the hair was measured by using scanning electron microscope. After 21 days of the experiment, mice treated with 2.5% mineral water showed the preferable effect on the number of hair, length, and thickness compared to the PC group and other concentration groups. However, the positive control minoxidil has no mineral containing ingredient but it has strong activity in hair growth. In our study, we found minoxidil had shown less active in hair growth effects in SKH-1 hairless mice. These results suggest that the using of optimum concentration of mineral rich spring water might have a remarked hair growth promoting effect, as observed morphologically. Collectively, according to our studies, we hypothesized that the topical application of mineral rich spring water might represent a novel strategy for the management and therapy for hair falling purpose. However, furthermore, studies could be more assured this hair growth promoting effects.

목차

ABSTRACT
 Introduction
 Materials and Methods
  1. Materials
  2. Experimental Animals
  3. Hair number and length determination
  4. Measurement of hair thickness
  5. Statistical analysis
 Results
  1. Measuring the hair number
  2. Measuring the hair length
  3. Measuring the hair thickness
 Discussion
 Acknowledgment
 Conflict of interest
 References

키워드

저자

• Rahima Begum [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Department of Global Medical Science, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea ]
• Jesmin Ara [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Department of Global Medical Science, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea ]
• Md Faruk Ahmed [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Department of Global Medical Science, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea ]
• Johny Bajgai [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Department of Global Medical Science, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea ]
• Ailyn Fadriquela [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Department of Global Medical Science, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea ]
• Kyu Jae Lee [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Institute for Poverty Alleviation and International Development, Yonsei University, Wonju, Gangwon 26493, Republic of Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국물학회지 [Korean Journal of Waters]

• 간기

  부정기

• pISSN

  2233-4653

• 수록기간

  2010~2021

• 십진분류

  KDC 539 DDC 628