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High Mineral Spring Water Promotes Skin Injury Healing in Hairless Mice

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  • 발행기관
    한국물학회 바로가기
  • 간행물
    한국물학회지 바로가기
  • 통권
    Vol.6 No.1 (2017.10)바로가기
  • 페이지
    pp.1-6
  • 저자
    Johny Bajgai, Kyu Jae Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A314367

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초록

영어
Wounds are common prevalent clinical problem found in day to day life. Although numerous studies have been conducted in this field but only few studies address about the mineral effect on wound healing process. To explore the therapeutic effect of the high mineral spring water (HMW) on the wound healing process, we carried out an animal injury model for that female SKH-1 mice were divided into five groups: normal control (NC, n=10), untreated control (NT, n=10), 100 % Pure HMW (PHMW, n=10) group, 10% HMW experimental (DHMW, n=10) and two round wounds (approximately 5 mm in diameter) total of 6 round wounds were punched into each side of the superior region of the posterior extremity by biopsy puncher to each mouse. We found that HMW spraying led to an enhanced healing speed compared to untreated control group. Reactive oxygen species was suppressed in both PHMW and DHMW group compared to NT group. Collectively, our results provide the evidence that HMW might be beneficial for the treatment of skin wound injury.

목차

ABSTRACT
 Introduction
 Materials and Methods
  1. Animals
  2. Preparation of Gyeokpo natural high mineral spring water
  3. Experimental Design
  4. Sample Preparation
  5. Determination of total Reactive Oxygen Species (ROS)
  6. Determination of Nitric Oxide (NO)
  7. Statistical Analysis
 Results
  1. Macroscopic analysis of skin wound injury treated by HMW shows injury
  2. Effect of HMW on total ROS on punched wound in hairless mice
  3. Effect of HMW on NO on punched wound injury in hairless mice
 Discussion
 Acknowledgment
 Conflict of interest
 References

키워드

Wound healing Mineral spring water Therapeutic effect Reactive oxygen species

저자

  • Johny Bajgai [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Department of Global Medical Science, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea ]
  • Kyu Jae Lee [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Institute for Poverty Alleviation and International Development, Yonsei University, Wonju, Gangwon 26493, Republic of Korea ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국물학회 [The Korean Water Society]
  • 설립연도
    2010
  • 분야
    자연과학>생물학
  • 소개
    기능수관련연구 경영과 정보를 공유, 일본 중국기능수재단 협회전문가 초빙하여 학회와의 정보교류 기능수관련 학회 및 학술지를 발행하여 물관련연구정보교류에 목적을 두고 있음.

간행물

  • 간행물명
    한국물학회지 [Korean Journal of Waters]
  • 간기
    부정기
  • pISSN
    2233-4653
  • 수록기간
    2010~2021
  • 십진분류
    KDC 539 DDC 628

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