Earticle

초록

영어

The oocyte undergoes various events during in vitro maturation (IVM) and subsequence development. One of the events is production of reactive oxygen species (ROS) that is a normal process of cell metabolism. But imbalances between ROS production and antioxidant systems induce oxidative stress that negatively affect to mammalian reproductive process. In vitro environments, in vitro matured oocytes have many problems, such as excessive production of ROS and imperfect cytoplasmic maturation. Therefore, in vitro matured oocytes still have lower maturation rates and developmental competence than in vivo matured oocytes. In order to improve the IVM and in vitro culture (IVC) system, antioxidants, vitamins were added to the IVM, IVC medium. Antioxidant supplementation was effective in controlling the production of ROS and it continues to be explored as a potential strategy to overcome mammalian reproductive disorders. Based on these studies, we expect that the use of antioxidants in porcine oocytes could improved maturation and development rates.

목차

ABSTRACT
 서론
 ROS
  Superoxide(O2—)
  Hydrogen Peroxide(H2O2)
  Hydroxyl Radical(․OH) (Haber–Weiss)
 항산화 물질
  Superoxide Dismutase(SOD)
  Glutathione Peroxidase (GPx)
  Catalase(Cat)
  Vitamins
  GSH (Glutathoine)
  Cysteine and Cysteamine (CSH)
  Taurine
 난자의 체외성숙과 배아발달동안 ROS의 영향
 난자의 체외성숙과 배아발달에 미치는 항산화제의 효과
 결론
 REFERENCES

키워드

저자

• 이원희 [ Won-Hee Lee | 강원대학교 동물생명과학대학 ]
• 박지은 [ Ji-Eun Park | 강원대학교 동물생명과학대학 ]
• 황보용 [ Yong Hwangbo | 강원대학교 동물생명과학대학 ]
• 김화영 [ Hwa-Young Kim | 강원대학교 동물생명과학대학 ]
• 이지은 [ Ji-Eun Lee | 강원대학교 동물생명과학대학 ]
• 강병범 [ Byeong-Buhm Kang | 강원대학교 동물생명과학대학 ]
• 정희태 [ Hee-Tae Cheong | 강원대학교 수의과대학 ]
• 양부근 [ Boo-Keun Yang | 강원대학교 동물생명과학대학 ]
• 박춘근 [ Choon-Keun Park | 강원대학교 동물생명과학대학 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Reproductive & developmental biology

• 간기

  계간

• pISSN

  1738-2432

• eISSN

  2288-0151

• 수록기간

  1977~2018

• 십진분류

  KDC 527 DDC 636