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Digging into Human Milk Oligosaccharides by Milk Pasteurization and Freeze-Dry

첫 페이지 보기
  • 발행기관
    한국당과학회 바로가기
  • 간행물
    한국당과학회 학술대회 바로가기
  • 통권
    2017 한국당과학회 동계학술대회 (2017.01)바로가기
  • 페이지
    pp.59-59
  • 저자
    Nari Seo, Tuyen Nguyen, Ye Rin Jin, Nam Mi Kang, Jae Han Kim, Hyun Joo An
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A294817

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원문정보

초록

영어
Human breast milk is frequently heated or frozen to restrain microbial growth. Nutrient compounds consisting of carbohydrates, proteins, and lipids are often affected by heating and freezing steps. In this study, we have monitored the change of human milk oligosaccharides (HMOs) after pasteurization and freeze-drying steps. HMOs are a family of structurally diverse unconjugated glycans that are highly abundant in human milk. It is well known that various structures of HMOs are associated with absorption, catabolism and biological functions such that contribute to immune maturation, organ development, and health microbial colonization. However, there is no previous study regarding chemical stability of HMOs during high temperature pasteurization and freeze-dried. Briefly, human milk samples from 3 mothers were pasteurized at 63℃ for 30minutes and freeze-dried at-83℃ for 5days, respectively. HMOs were enriched and profiled by mass spectrometry. Initially the composition and structure of HMOs was assigned by MALDI-TOF/TOF MS. Further, native HMOs were relatively quantified by PGC column-based LC/MS providing an enhanced separation of isomeric structure. More than 30 HMOs have been identified and quantified. We could confirm that pasteurization and freeze-drying of human milk does not influence chemical property of HMOs at all.

저자

  • Nari Seo [ Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Asia-Pacific Glycomics Reference Site ]
  • Tuyen Nguyen [ Department of Food and Nutrition, Chungnam National University ]
  • Ye Rin Jin [ Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Asia-Pacific Glycomics Reference Site ]
  • Nam Mi Kang [ College of Nursing Konkuk University ]
  • Jae Han Kim [ Department of Food and Nutrition, Chungnam National University ]
  • Hyun Joo An [ Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Asia-Pacific Glycomics Reference Site ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국당과학회 [Korean Society for Glycoscience]
  • 설립연도
    2006
  • 분야
    의약학>약학
  • 소개
    본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.

간행물

  • 간행물명
    한국당과학회 학술대회
  • 간기
    연간
  • 수록기간
    2006~2022
  • 십진분류
    KDC 517 DDC 614

이 권호 내 다른 논문 / 한국당과학회 학술대회 2017 한국당과학회 동계학술대회

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