Earticle

초록

영어

Background: This study is to investigate the prescription patterns and factors related to the number of medications treating chronic obstructive pulmonary disease (COPD) in patients under 65 years old according to GOLD guidelines. Methods: We retrospectively analyzed the medical records of patients aged 40-64 years with a diagnosis of COPD from January to March 2016. Patients were classified by combined assessment of COPD (grades A, B, C, D) using spirometry, exacerbation history, mMRC, and/or CAT results. We analyzed prescribed medications, treatment options and factors related to the numbers of COPD medications. Results: The total number of prescriptions were 251. About 35.5% of patients were classified as GOLD A, 34.2% as GOLD B, 17.1% as GOLD C and 13.2% as GOLD D. Inhaled bronchodilator was prescribed for 86.9% of patients and the most frequent COPD medication was longacting muscarinic antagonist (LAMA) followed by inhaled corticosteroids/long acting beta agonist (ICS/LABA). The majority of low risk patients (GOLD A/B) were prescribed a monotherapy with LAMA or LABA. For high risk patients (GOLD C/D), combination treatment with ICS+LAMA+LABA was mostly prescribed. The 21.2% of patients in GOLD D received systemic corticosteroid. The average number of medications per prescription was 3.7, and this number increased with increasing COPD grade, COPD duration and lung function reduction (FEV1, FEV1/FVC). Conclusion: Generally high adherence to GOLD guideline recommendations was reported. Given the progressive nature of the disease, results suggest that closer attention to respiratory symptoms for early detection, diagnosis, and appropriate treatment of COPD is warranted.

목차

ABSTRACT
 연구방법
  연구대상 및 조사항목
  평가 항목 및 평가 기준
  통계 분석
  피험자 보호
 연구 결과
  연구 대상의 특징
  처방 현황 분석
  COPD 치료약제 이외의 약물의 처방현황
  약 품목 수와 의약품 사용 관련 요인과의 상관관계 분석
 고찰
 참고문헌

키워드

저자

• 문채원 [ Chae-won Moon | 서울성모병원 약제부, 이화여자대학교 임상보건과학대학원 ]
• 나현오 [ Hyun-O Ra | 가톨릭대학교 의과대학 ]
• 이정연 [ Sandy Jeong Rhie | 이화여자대학교 임상보건과학대학원, 이화여자대학교 약학대학·생명약학부 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615