Earticle

초록

영어

Objective: Although guideline recommends beta blockers (BBs) as first line antianginal agent and calcium channel blockers (CCBs) as alternatives after percutaneous coronary intervention (PCI), the prescription patterns in real practice are not in accordance with the guideline. We aimed to investigate the prescribing patterns of primary antianginal drug and relating factors in patients who underwent PCI. Methods: Patients who have undergone PCI without myocardial infarction (MI) from November 2012 to June 2014 and followed up at least one year in a tertiary teaching hospital were included. Prescribing patterns of primary antianginal drug before, at the time of, and one year after PCI were described. Factors affecting drug selection, and their relationship with incidence of clinical outcomes defined as MI and repeated PCI, unscheduled admission or visit related with heart problem were analyzed with multivariate logistic regression. Results: A total of 506 patients were included and as primary antianginal drugs, BB, CCB, and both were prescribed in 32.2%, 24.5%, and 17.8% of patients, respectively. Also, neither BB nor CCB was prescribed at the time of PCI in 25.5% of patients. Compared with BB, CCBs were more likely prescribed in patients who had hypertension (Odds Ratio, OR 2.18, 95% confidence interval, CI 1.16-4.07), use of same class before PCI (OR 7.18, 3.37-15.2) and concomitant angiotensin receptor blocker (ARB) use (OR, 1.92, 95% CI 1.10-3.33). Incidence of clinical outcomes were not significantly greater in patients who prescribed CCB compared with BB at the time of PCI (aOR 1.32, CI 0.65-2.68). Conclusion: This study demonstrated that half of the patients who underwent PCI were prescribed BB. CCB were favored in patients with hypertension, use of same class before PCI, and concomitant ARB use. Significant difference in clinical outcome was not observed between BB and CCB selection as primary antianginal drug.

목차

ABSTRACT
 서론
 연구 방법
  연구설계 및 연구대상
  자료수집 및 분석
  통계분석
 연구 결과
  환자특성
  관상동맥중재술 시행 전 후 처방패턴
  관상동맥중재술 시행 후 일차 항협심증 약제 선택에 영향을 미치는 요인
  관상동맥중재술 후 항협심증 일차 약제 선택이 임상결과에 미치는 영향
 고찰
 참고문헌

키워드

저자

• 노선영 [ Sun Young Noh | 서울대학교병원 약제부 ]
• 조윤희 [ Yun Hee Jo | 서울대학교병원 약제부 ]
• 조윤숙 [ Yoon Sook Cho | 서울대학교병원 약제부 ] Co-corresponding author
• 한현주 [ Hyeon Joo Hahn | 서울대학교병원 약제부 ]
• 이해영 [ Hae-Young Lee | 서울대학교병원 순환기내과 ]
• 이주연 [ Ju-Yeun Lee | 한양대학교 약학대학 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615