Earticle

초록

영어

PLA and PLGA have been extensively used for controlled drug delivery and used to fabricate device for tissue engineering. The objective of the present study was to know the effect of different molecular weight of PLLA and PLLGA. PLLA and PLLGA membrane was prepared using a solvent-casting method. In vitro degradation of the blank membrane was characterized by techniques including NMR, SEM, BET. And examined the degradation of PLA-PGA copolymer at different temperature range. The lower molecular weight, the more porosity and the smaller pore size. The degradation ratio of membrane increased with increasing test temperature.

목차

Abstract
 1. Introduction
 2. Materials and Methods
  2.1. Materials
  2.2 Preparation of Membranes
  2.3. In vitro Degradation of Membranes
  2.4. Differential Scanning Calorimeter (DSC)
  2.5. Scanning Electron Microscopy (SEM)
  2.6. Brunauer Emmett Teller (BET)
 3. Results
  3.1 The Glass Transition Temperature of Membranes
  3.2 Morphological of Blank Membranes
  3.3 Pore Size and Porosity of PLLA and PLLGA Membranes
  3.4 Weight loss of PLLGA membranes
  3.5 Media pH Measurements
 4. Conclusions
 References

키워드

저자

• Yuying Xie [ Dept. Of Environment Eng., Sunmoon University,Korea ]
• Jong-soon Park [ GLO-ONE Co Ltd. Korea ]
• Soon-kook Kang [ Dept. Of Environment Eng., Sunmoon University,Korea ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  International Journal of Bio-Science and Bio-Technology

• 간기

  격월간

• pISSN

  2233-7849

• 수록기간

  2009~2016

• 등재여부

  SCOPUS

• 십진분류

  KDC 505 DDC 605