Earticle

초록

영어

As a one of unsaturated fatty acid, polyunsaturated fatty acids (PUFAs) have multiple actions: as precursor of prostaglandins (PGs), steroid hormone synthesis and energy production in animal reproduction. PUFAs, which include omega-3 (n-3) and omega-6 (n-6), are derived from the diet and changed by diet, species, breed and season. The plasma membrane of spermatozoa in mammals contain various PUFAs. These composition of PUFAs regulate the membrane fluidity and cause lipid peroxidation via generation of reactive oxygen species (ROS). Induced lipid peroxidation by ROS decreased viability and motility of spermatozoa, and it is reduced by addition of antioxidant and low concentration of PUFAs. Because oocytes of animal have a high lipid components, process of oocyte maturation and embryo development are influenced by PUFAs. In in vitro study, oocyte maturation, embryo development, intracellular cAMP and MAPK activity were increased by treatment of n-3 α-linolenic acid (ALA) during maturation, whereas n-6 linoleic acid (LA) negatively influenced. Also, inhibition of fatty acid metabolism in oocyte influenced blastocyst formation of cattle. PGs are synthesized from PUFAs and various PUFAs influence PGs via regulation of PG-endoperoxide synthase (PTGS). Steroid hormone synthesis from cholesterol is regulated by expression of steroid acute regulator (StAR) protein and mRNA. Exogenous n-3 and n-6 PUFAs altered sex hormone in animal through stimulate or inhibit StAR activity. Because PUFAs altered PG and steroid hormone synthesis, follicular development was influenced by PUFAs. This effect of unsaturated fatty acid could provide information for improvement of reproductive ability in animals.

목차

ABSTRACT
 INTRODUCTION
 UNSATURATED FATTY ACIDS AND SPERMATOZOA
 UNSATURATED FATTY ACID AND OOCYTE AND EMBRYO DEVELOPMENT
 UNSATURATED FATTY ACIDS AND REPRODUCTIVE EVENTS
  Prostaglandin Synthesis
  Steroid Synthesis
  Follicle Development
 CONCLUSION
 REFERENCES

키워드

저자

• Yong Hwangbo [ College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Korea ]
• Hwa-Young Kim [ College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Korea ]
• Yu-Rim Lee [ College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Korea ]
• Seung Tae Lee [ College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Korea ]
• EunSong Lee [ College of Veterinary Medicine, Kangwon National University, Chuncheon 24341, Korea ]
• Hee-Tae Cheong [ College of Veterinary Medicine, Kangwon National University, Chuncheon 24341, Korea ]
• Boo-Keun Yang [ College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Korea ]
• Choon-Keun Park [ College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Reproductive & developmental biology

• 간기

  계간

• pISSN

  1738-2432

• eISSN

  2288-0151

• 수록기간

  1977~2018

• 십진분류

  KDC 527 DDC 636