Earticle

초록

영어

Background: Depression is the leading cause of lowering the quality of life of cancer patients and lung cancer is the most likely to cause depression. It is necessary to find out depression-related factors in lung cancer patients. Methods: The study was a retrospective cohort study using medical records, and was a non-equivalent comparison group design. It involved patients diagnosed of lung cancer at the Konkuk University Medical Center from January to December 2012. Between antidepressants prescription group and non prescription group, socio-demographic factors, clinical factors, treatment-related factors and other factors were analyzed statistically. Results: Antidepressant prescription group consisted of 23 people and non-prescription group of 206 people. Prescription rate of quetiapine was the highest 47.8% (11/23), followed by escitalopram (43.5%, 10/23), amitriptyline and trazodone (30.4%, 7/23). The prescription group was prescribed with an average of 1.9 antidepressants. Antidepressants were prescribed after average of 248 days from lung cancer diagnosis and prescription period per patient was average 177.5 days. According to the result of univariate logistic regression analysis between 2 groups, factors such as number of outpatient visit, number of admission, days of hospitalization, sleep disorder, and comorbidity were found to be statistically significant (p < 0.05). However, According multivariate logistic regression analysis showed that number of admission, days of hospitalization and sleep disorder were statistically significant (p < 0.05) excluding comorbidity. Conclusion: About 10% of lung cancer patients had received a prescription for antidepressants after lung cancer diagnosis. A sleep disorder, number of hospitalization and length of stay were identified as factors influencing the prescribing antidepressants.

목차

ABSTRACT
 연구 방법
  대상환자 및 자료수집
  자료의 수집 및 분석
  자료 분석 방법
 결과
  연구 대상자 특성 및 항우울제 처방현황
  항우울제 처방군과 비처방군 사이의 각 요인에 대한 교차분석 결과
  항우울제 처방군과 비처방군 사이의 각 요인에 대한 단변량 로지스틱 회귀분석 결과
  항우울제 처방군과 비처방군 사이의 다변량 로지스틱 회귀분석 결과
 고찰
 결론
 참고문헌

키워드

저자

• 성경은 [ Kyeong Eun Sung | 건국대학교병원 약제부, 중앙대학교 약학대학 ]
• 정경혜 [ Kyeong Hye Jeong | 중앙대학교 약학대학 ]
• 김애리 [ Ae Ri Kim | 건국대학교병원 약제부 ]
• 김은영 [ Eun Young Kim | 중앙대학교 약학대학 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615