[PURPOSE] The present study examined old male adults to compare physical fitness and cytokine concentrations between obese and non-obese men, and observed post-exercise training changes. [METHODS] Subjects were eighty old male adults, and were divided into an obese group (n =40) and a non-obese group (n=40) based on a BMI of 25 kg/m2. Body composition, muscular strength, cardiopulmonary function, blood TNF-α, IL-6, and IL-10 concentrations were compared between obese group and non-obese group, and then the changes in these parameters were compared after a regular 12-week exercise training. [RESULTS] The overall abdominal fat, subcutaneous fat, and visceral fat areas were significantly larger values in the obese group (p<.05). The muscle-to-fat area ratios in both the abdomen and thigh were significantly lower in the obese group (p<.05). The abdominal and thigh fat areas significantly decreased after exercise training in both groups (p<.05), and the muscle-to-fat area ratios in both the abdomen and thigh significantly increased in both groups (p<.05). The obese group had significant higher blood IL-6 and TNF-α concentrations (p<.05), and significant lower grip strength per kilogram of body weight, PEI obtained from the Harvard step test, and sit-and-reach test score (p<.05). Both groups had significantly enhanced blood TNF-α concentration, grip strength, back muscular strength, and grip or back muscular strengths per kilogram of body weight after exercise training (p<.05). Post-exercise reduction in TNF-α was inversely correlated with increased muscle-to-fat area ratio in the thigh and increased back muscular strength (p<.05). [CONCLUSIONS] The obese group exhibited relative reductions in muscle mass and muscle strength, and had higher blood IL-6 and TNF-α concentration than those in the non-obese group. However, the findings of this study also indicate that these phenomena could be prevented by exercise training. Post-exercise training reduction in blood TNF-α level is significantly correlated with reduction in body fat, increased muscle-to-fat area ratios in the abdomen and thigh, and increased muscular strength. Based on this finding, TNF-α level could be used as an important inflammatory marker related to sarcopenic obesity that occurs during aging.
목차
ABSTRACT Introduction Methods Subjects Measurements Exercise training program Statistical Analyses Results Discussion Conclusions References
본회는 인체의 운동에 관련된 연구 활동을 통하여 운동학의 학문적 체계를 정립하고 운동을 통하여 인간의 건강과 행복을 추구하는데 필요한 실용적 지식과 기술을 개발, 보급함을 목적으로 한다.
본회는 위의 목적을 달성하기 위하여 다음과 같은 사업을 수행한다.
1. 운동의 본질과 운동참여율제고를 위한 철학적, 역사적, 기술적, 실험적, 창의적 연구
2. 운동 시설ㆍ프로그램의 개발, 보급 관련 연구
3. 운동사 양성 및 배치 방안에 관한 정책 개발
4. 전문서적 간행
5. 학술지 발행 및 배포
6. 학술정보 수집 및 교류, 보급
7. 관련 시설 및 기관, 단체에 대한 자문, 건의, 협조
8. 기타 본 회 목적 달성에 필요한 사업