Earticle

초록

영어

In order to develop methods to measure dioxin-like compounds in human serum. In addition to measurement of dioxin-like compounds, we established the method for sampling and storage. The volume of serum for analysis dioxin-like compounds was about 30ml(70ml of whole blood). The serum were stored in refrigerator until analysis. Serum(20-30g) was treated for 4h with 2N KOH/EtOH solution. The solution was extracted with n-hexane and the hexane phase was treated with sulfuric acid. The hexane phase was concentrated and applied to columns packed with multi layer silica gel, AgNO3, alumina and active carbom column. The 6 kinds of purification Method were applied to determine Dioxin-like compounds. The recovery of the dioxin were high in method 1(treated with sulfuric acid and multi-layer silica gel column, alumina column, active carbon column). And method 4(only multi-layer silica gel column) can remove the matrix of blood serum as effectively as a multi-layer silica gel column.

목차

Abstract 
 I. 서 론
 II. 연구내용 및 실험방법
  1. 다이옥신 분석을 위한 생체시료
  2. 혈액시료의 분석조건
  3. 혈액 중 지질성분 분석
  4. 기기분석조건
 III. 연구결과 및 고찰
  1. 다이옥신 분석결과
 IV. 결 론
 References

키워드

저자

• 박충희 [ Choong-Hee park | 국립환경과학원 환경보건안전부 환경역학과 ]
• 강택신 [ Tack-Shin Kang | 국립환경과학원 환경보건안전부 환경역학과 ]
• 이종화 [ Jong-Hwa Lee | 국립환경과학원 환경보건안전부 환경역학과 ]
• 김대선 [ Dae-Seon Kim | 국립환경과학원 환경보건안전부 환경역학과 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국EHS평가학회지 [KOREAN JOURANL OF EHS ASSESSMENT ; ENVIRONMENT HEALTH SAFETY]

• 간기

  계간

• pISSN

  1598-9526

• 수록기간

  2003~2007

• 십진분류

  KDC 330 DDC 363