Earticle

초록

영어

We have employed X-ray photoelectron spectroscopy (XPS) technique to examine the combined effects of low-energy electron (LEE) irradiation and Fe3+ ion on DNA damage. pBR322 plasmid DNA extracted from E. coli ER2420 was used for preparing DNA-Fe3+ sample. The C1s XPS spectra were scanned for LEE-irradiated and LEE-unirradiated samples and then curve-fitted. For the samples with LEE irradiation only or with Fe ion only, no significant changes from pure DNA samples were observed - a single effect of either Fe3+ ion or LEE irradiation did not cause a significant damage. However, when these two components were combined, the DNA damage was increased quite significantly, compared to the sum of DNA damages caused by Fe3+ ion and by LEE irradiation independently. This observation is consistent with our previous results [Radiat. Res. 177, 775 (2012)] which was done using gel-electrophoresis technique. Partial interpretation of the observed spectrum peaks was also attempted.

목차

Abstract
 1. INTRODUCTION
 2. MATERIALS AND METHODS
 3. RESULTS AND DISCUSSION
 4. CONCLUSION
 REFERENCES

키워드

저자

• Hyung-Ah Noh [ Physics Department, Chungnam National University, Daejeon 305-764 Korea ]
• Yeun-Soo Park [ National Fusion Research Institute, Osikdo-dong, Gunsan, 573-540, Korea ]
• Hyuck Cho [ Physics Department, Chungnam National University, Daejeon 305-764 Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629