Earticle

초록

영어

This study was designed to assess whether the conventional tangential technique, using a multileaf collimator (MLC), allows a reduced dose to the organs at risk (OAR) in breast radiation therapy. A total of forty right and left 20 for each breast cancer patients that underwent radiation therapy after breast conserving surgery were included in this study. For each patient, the planning target volume (PTV) and OAR (heart, left anterior descending artery (LAD), liver and lung) were defined and dose distribution were produced for conventional tangential beams using 6 MV photons. The treatment plans were made using the following two techniques for all patients. For the first plan (P1), MLC was designed to shield as much of OAR as possible without compromising the coverage of PTV. In the second plan (P2), the treatment plan was created without using MLC. Dose-volume histograms for OARs were calculated for all plans. For left breast cancer, the percentage of maximum dose (Dmax%) and mean dose (Dmean%) of OARs (heart and LAD) were calculated, and for right breast cancer, the percentage of the mean dose (Dmean%) of the liver was calculated. The Dmean% of the lung was calculated in all patients. The mean values of Dmax% of the heart (86.9±19.5% range, 35.1-100.6%) in P1 were significantly lower than in P2 (98.3±3.4% range, 91.7-105.2%) (p=0.001). The mean values of Dmax% of LAD (78.4±22.5% range, 26.5-99.7%) in P1 was significantly lower than in P2 (93.3±8.1% range, 67.9-102.1%) (p<0.001). In P1, the mean values of Dmean% of the liver (4.8±2.0%) were significantly lower than in P2 (6.2±2.5%) (p<0.001). The mean values of Dmean% of the lung were significantly lower in P1 (9.3±2.3%) than in P2 (9.7±2.4%) (p<0.001). P1, by using MLC, allows a significantly reduced dose to OAR compared with P2. We can suggest that it is reasonable to routinely use MLC in the conventional tangential technique for breast radiation therapy considering the primary tumor location.

목차

Abstract
 1. INTRODUCTION
 2. MATERIALS AND METHODS
  2.1 Image Acquisition for RT planning and Treatment
  2.2 Delineation of Target and Organ at risk
  2.3 Treatment Planning and Analysis
 3. RESULTS AND DISCUSSION
  3.1 Normal Tissues (OARs)
  3.2 Target Volumes (PTV)
 4. CONCLUSION
 REFERENCES

키워드

저자

• KYU CHAN LEE [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ]
• SEOK HO LEE [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ] Corresponding author
• SEUNG HEON LEE [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ]
• KIHOON SUNG [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ]
• SO HYUN AHN [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ]
• JINHO CHOI [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ]
• KAP SANG DONG [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ]
• HYO JIN KIM [ Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University ]
• YONG SEON CHUN [ Department of Surgery, Gil Medical Center, School of Medicine, Gachon University ]
• HEUNG KYU PARK [ Department of Surgery, Gil Medical Center, School of Medicine, Gachon University ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629