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Expression Patterns of Apoptosis, Adhesion and Immune related Proteins in Uterine Endometrium with Normal Ovarian Follicles and Ovarian Cyst in Hanwoo

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    Reproductive & developmental biology 바로가기
  • 통권
    Volume 38 No 4 (2014.12)바로가기
  • 페이지
    pp.165-170
  • 저자
    Jin-Woo Kim, Yong-Hee Lee, Sung-Kyu Chae, Sung-Hun Min, Jae-Hyun Ahn, Geon-Yeop Do, Byung Oh Kim, Humdai Park, Deog-Bon Koo
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A237177

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원문정보

초록

영어
Cows may suffer impaired ovarian function, often accompanied by reduced conception rates and increased embryonic loss. Cystic ovarian disease (COD) is one of the most frequently diagnosed gynecological findings in dairy cattle. It causes temporary infertility and is likely to affect reproduction as well as production parameters in cattle. Therefore, the purpose of this study was to determine the expression patterns of apoptosis (Bcl-2, Bax), implantation (E-cadherin) and immune related proteins (TNF-α, IL-10) in uterine endometrium of Hanwoo (Korean native cattle) with ovarian cyst and normal ovarian follicles. In the Western blot analysis, the expression of anti-apoptotic Bcl-2 protein was significantly higher in endometrium with normal ovarian follicles, whereas expression of pro-apoptotic Bax protein was significantly lower. Also, the expressions of E-cadherin and TNF-α proteins were significantly higher in uterine endometrium with normal ovarian follicles. On the other hand, the expression of IL-10 protein was significantly lower in uterine endometrium with normal ovarian follicles. Taken together, our results provided that the expressions of apoptosis, adhesion and immune related proteins in uterine endometrium with ovarian cyst were showed the aberrant patterns, and we suggest that different expression changes of these proteins may be affect to pregnancy ability of cattle.

목차

ABSTRACT
 INTRODUCTION
 MATERIALS AND METHODS
 RESULTS
 DISCUSSION
 REFERENCES

키워드

Protein expression Endometrium Ovarian cyst Cattle

저자

  • Jin-Woo Kim [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ]
  • Yong-Hee Lee [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ]
  • Sung-Kyu Chae [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ]
  • Sung-Hun Min [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ]
  • Jae-Hyun Ahn [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ]
  • Geon-Yeop Do [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ]
  • Byung Oh Kim [ School of Food Science & Biotechnology, College of Agriculture & Life Sciences, Kyungpook National University, Daegu 702-701, Korea ]
  • Humdai Park [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ]
  • Deog-Bon Koo [ Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    Reproductive & developmental biology
  • 간기
    계간
  • pISSN
    1738-2432
  • eISSN
    2288-0151
  • 수록기간
    1977~2018
  • 십진분류
    KDC 527 DDC 636

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