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The effect of reduced water on Nc/Nga atopic dermatitis mice

첫 페이지 보기
  • 발행기관
    한국물학회 바로가기
  • 간행물
    한국물학회 학술대회 바로가기
  • 통권
    2013 International Healthy Drinking Water Symposium (2013.03)바로가기
  • 페이지
    pp.185-185
  • 저자
    Yang-SukYoon, Ma Easter Joy Sajo, Dong-hee Kim, Cheol-so Kim, Soo-ki Kim, Kyu-Jae Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A234184

원문정보

초록

영어
Atopic dermatitis(AD) is chronic pruritic inflammatory skin disease. Patients with severe or persistent AD and their families suffer from significant impairment in their quality of life. AD places a heavy economic burden not only on patients and their families, but also on society in general. AD ha s been related inflammation and oxidative stress. immunological abnormalities is causing more severe AD lesion. HRW(Hydrogen reduced water) have antioxidant properties, and can exert anti-inflammatory effects. The purpose of this study was to determine the drinking effect of the HRW with the properties of high pH and low ORP in mice induced AD skin lesions. Mice were sensitized using 2,4-dinitrochlorobenzene(DNCB) to cause AD-like skin lesions in NC/Nga mice, and taken Hydrogen reduced water(HRW group) or purified water(PW group). We found that Interlukin(IL)-1β, IL-2, IL-4, IL-5, IL-10, IL-12(p70), Granulocyte macrophage-colony stimulating factor (GM-CSF), Interferon-gamma (INF-r), and Tumor necrosis factor –alpha (TNF-a) werw less in the HRW group compared to the PW group. These results suggest that regular drinking HRW with the properties of high pH and low ORP has a positive effect on AD skin lesions.

키워드

alkaline reduced water atopic dermatitis DNCB inflamation immune

저자

  • Yang-SukYoon [ Department of Environmental Medical Biology and Institute for Poverty Alleviation and International Development (IPAID) Yonsei University Korea ]
  • Ma Easter Joy Sajo [ Department of Environmental Medical Biology and Institute for Poverty Alleviation and International Development (IPAID) Yonsei University Korea ]
  • Dong-hee Kim [ Department of Environmental Medical Biology ]
  • Cheol-so Kim [ Department of Microbiology, Wonju college of Medicine ]
  • Soo-ki Kim [ Department of Microbiology, Wonju college of Medicine ]
  • Kyu-Jae Lee [ Department of Environmental Medical Biology and Institute for Poverty Alleviation and International Development (IPAID) Yonsei University Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국물학회 [The Korean Water Society]
  • 설립연도
    2010
  • 분야
    자연과학>생물학
  • 소개
    기능수관련연구 경영과 정보를 공유, 일본 중국기능수재단 협회전문가 초빙하여 학회와의 정보교류 기능수관련 학회 및 학술지를 발행하여 물관련연구정보교류에 목적을 두고 있음.

간행물

  • 간행물명
    한국물학회 학술대회
  • 간기
    부정기
  • 수록기간
    2013~2024
  • 십진분류
    KDC 539 DDC 628

이 권호 내 다른 논문 / 한국물학회 학술대회 2013 International Healthy Drinking Water Symposium

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