Earticle

초록

영어

Objectives: This paper was aimed to investigate the adhesion control standards of pain relieving patch (PRP) drugs and to survey it’s adverse effects on the skin of patients for safe use of PRP drugs. Methods: In this study, the related documents of PRP drugs of Korea pharmacopoeia (KP), United States pharmacopoeia (USP), Japanese Pharmacopoeia (JP), European pharmacopoeia (EP), and information web sites of the Ministry of Food and Drug Safety (MFDS) were surveyed. Also, the past and current labeling of PRP drugs marketed in the pharmacy was investigated and compared. Results: In KP and JP, the lower limit standard for PRP's adhesion control is established, but the upper limit standard is not designated. In USP and EP, neither the lower nor upper limit standard is established. The main reasons of skin adverse effects are considered as inherent adverse reactions of the applied drugs for PRP. Another reason is involved in patient's medication mistakes related to PRP's adhesion control, respiratory depression of skin according to physical skin closure, and microbial growth, etc. Conclusion: For safe use of PRP drugs, we proposed ensured guidelines like additional instructions of pharmacist's prescription and detailed labeling systems for usage of PRP drugs applied on skin.

목차

Abstract
 연구 방법
 연구 결과
  국내·외 피부 부착용 제제의 분류와 정의
  국내·외 피부 부착용 제제에 대한 점착력 관리기준
  피부 부착용 제제 사용에 따른 피부 부작용의 원인
  점착력과 피부 부작용의 상관관계
  시중 유통품목의 안전사용표시 실태조사
 고찰
 감사의 말씀
 참고문헌

키워드

저자

• 김지연 [ Ji Yeon Kim | 조선대학교 대학원 식품의약학과 ]
• 김광준 [ Kwang Joon Kim | 조선대학교 약학대학 약학과 ]
• 박상욱 [ Sang-Wook Park | 조선대학교 대학원 식품의약학과 ]
• 방준석 [ Joon Seok Bang | 숙명여자대학교 임상약학대학원 ]
• 이원재 [ Wonjae Lee | 조선대학교 대학원 식품의약학과, 조선대학교 약학대학 약학과 ] Correspondence to

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615