Earticle

초록

영어

Microbial biofilms on biomaterial implant surfaces or devices are troublesome, since biofilm organisms are protected by matrix of exopolymeric substances, impenetrable for most antibiotics and immune cells. It is established that bacterial adhesion to surface is required for colonization and subsequent biofilm formation. The adherent state is important for bacterial survival and development of infection. Therefore, prevention of bacterial adhesion and biofilm growth on implant surfaces should ultimately prevent the occurrence of infection. Egg white was considered to play an important role in resistance against bacteria for developing embryo mainly during early incubation. Utilization of egg white as a coating to prevent bacterial adhesion and biofilm growth on biomaterials implants is novel. Here, we studied the effect of Hen egg white as a coating to surface, on bacterial (Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli) adhesion and biofilm growth. We report that a significant reduction in bacterial adhesion was observed for S.aureus on egg white coated surface compared to control (no egg white coating). Whereas P. aeruginosa and E. coli, do not show any significant difference compared to control. When bacteria were allowed to grow in the presence of egg white, a significant reduction in growth was observed on all bacteria compared to control. Thus Hen egg white potentially used as biological coating on implants for prevention of bacterial adhesion and biofilm formation.

목차

Abstract
 1. Introduction
 2. Materials and Methods
 3. Results and Discussion
 4. Conclusion
 Acknowledgements
 Conflict of Interest
 References

키워드

저자

• Sivaramakrishnan Rajaraman [ Department of Biomedical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Kalavakkam- 603110, Tamilnadu, India ]
• Guruprakash Subbiahdoss [ Department of Biomedical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Kalavakkam- 603110, Tamilnadu, India ] Corresponding Author
• Padmanaban Patchirajan [ Marine reptile section, Zoological survey of India, Marine Biology Regional Centre, Chennai – 600028, Tamilnadu, India ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  International Journal of Bio-Science and Bio-Technology

• 간기

  격월간

• pISSN

  2233-7849

• 수록기간

  2009~2016

• 등재여부

  SCOPUS

• 십진분류

  KDC 505 DDC 605