Role of Pico Second PEF On Osteoblast Intra organelle Nanoporation
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- 발행기관
- 보안공학연구지원센터(IJAST) 바로가기
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- 간행물
- International Journal of Advanced Science and Technology 바로가기
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- 통권
- Vol.67 (2014.06)바로가기
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- 페이지
- pp.43-58
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- 저자
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- 언어
- 영어(ENG)
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- URL
- https://www.earticle.net/Article/A229863
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
- 영어
- This paper presents the effect of pico pulse electric field on intra organelle nano poration of multi layer osteoblast cell placed in a 3D non uniform microfloudic chip composed of bi metallic heterogeneous micro electrode under the influences of smart control FPGA based pico pulse generator and images of intra organelle nanoporation are recognized by neural fuzzy network. It is observed that When the micro pulse is applied the cell starts to response but it is unable to penetrate the intra cellular nucleus- membrane where as the expected results will come when the Pico pulse is applied on the cell, a number of nana pores are generated on the intra organelle and chemicals are entered into the cell. It is also exposed that the key parameter of nanoporation such as intra organelle voltage, pore radius, pore density, pressure, surface tension and ion uptake are externally controlled by user defined hybrid 3D micro chip and FPGA based pico pulse generator. The application of neural fuzzy network for succesfull reorganization of nanoporative image is completely explore.
목차
Abstract
1. Introduction
2. Analytical Study
2.1 Effect of pico pulse on the induced intra organelle voltages
2.2 Effect of pico pulse on the radius of nanopores:
2.3 Effect of pico pulse on the intra organelle pore current
2.4 Effect of pico pulse on the intra organelle pressure:
2.5 Effect of pico pulse on the intra organelle surface tension
2.6 Effect of pico pulse on the intra organelle pore density
3. Used Parameter
4. Materials and Methods
4.1 Pico Pulse Exposer system
4.2 Sample Preparations
4.3 Set up for intrigrated intraorganelle nanoporation system
4.4 Biological experiments
4.5 Experimental Data
4.6 Observations
4.7 Application of neuro fuzzy network for image reorganization of intra organelle nanoporation
5. Results and Discussion
6. Conclusion
Acknowledgements
References
키워드
Picoseconds Pulsed Electric Field (psPEF) Bi metallic electrode intrigrated bio Micro chip Dense Osteoblast cell Intra- organelle nanoporation. Neural fuzzy network저자
간행물 정보
발행기관
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- 발행기관명
- 보안공학연구지원센터(IJAST) [Science & Engineering Research Support Center, Republic of Korea(IJAST)]
- 설립연도
- 2006
- 분야
- 공학>컴퓨터학
- 소개
- 1. 보안공학에 대한 각종 조사 및 연구 2. 보안공학에 대한 응용기술 연구 및 발표 3. 보안공학에 관한 각종 학술 발표회 및 전시회 개최 4. 보안공학 기술의 상호 협조 및 정보교환 5. 보안공학에 관한 표준화 사업 및 규격의 제정 6. 보안공학에 관한 산학연 협동의 증진 7. 국제적 학술 교류 및 기술 협력 8. 보안공학에 관한 논문지 발간 9. 기타 본 회 목적 달성에 필요한 사업
간행물
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- 간행물명
- International Journal of Advanced Science and Technology
- 간기
- 월간
- pISSN
- 2005-4238
- 수록기간
- 2008~2016
- 십진분류
- KDC 505 DDC 605
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