Squids and Hydroids utilize organic biopolymers as building blocks to form their load-bearing tissues. These polymeric tissues are appealing for their unusual physical and mechanical properties, including high hardness and stiffness, toughness, and low density. Here, the biochemical structure and composition of the hydroid perisarc of Aglaophenia latirostris Nutting, 1900, were investigated. Chitin, protein, and melanin, were found to represent 10, 17 and 60 wt% of the perisarc, respectively. Interestingly, similar to the adhesive and coating of marine mussel byssus, a DOPA (3, 4-dihydroxyphenylalanine) containing protein and iron were detected in the perisarc. A resonance Raman microprobe analysis of perisarc indicates the presence of DOPA-iron (III) complexes in situ, but it remains to be determined whether the DOPA-iron (III) interaction plays a cohesive role in holding the protein, chitin and melanin networks together. We also designed a method to improve the mechanical properties of chitosan in wet conditions and minimized the swelling behavior of chitosan film due to water adsorption by mimicking the sclerotization of hydroid perisarc and squid beaks, i.e., catechol-meditated cross-linking. The biomimetic chitosan composite film was prepared by mixing chitosan with L-3,4-dihydroxyphenylalanine (DOPA) as a catecholic cross-linker and sodium periodate as an oxidant. The catechol-meditated cross-linking provided a 7-fold enhancement in the stiffness in wet conditions compared to pure chitosan films and reduced the swelling behavior of the chitosan film. This strategy expands the possible applications for the use of chitosan composites as load-bearing biomaterials.
목차
1. 학력 2. 경력 3. 주요 연구분야/공동연구 가능분야 4. 수행중인 연구과제 5. 대표 논문/특허 6. 보유 기술, 장비 혹은 제공 가능한 물질(표준물질, 저해제, 효소, 항체, 유전자, 세포주등) Squid beak and hydroid perisarc inspired chitin/chitosan composite Acknowledgement
저자
황동수 [ Dong Soo Hwang | 포항공과대학교 해양대학원/환경공학부, 조교수 ]
Dongyeop Oh [ School of Interdisciplinary Bioscience and Bioengineering Pohang University of Science and Technology,790-784, Pohang,South Korea ]
Ekavianty Prajatelistia [ School of Interdisciplinary Bioscience and Bioengineering Pohang University of Science and Technology,790-784, Pohang,South Korea ]
본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.